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This case report describes a 29-year-old woman diagnosed with both systemic lupus erythematosus and Graves' disease, illustrating the occurrence of autoimmune polyendocrine syndromes with specific combinations of autoimmune disorders.

This case report documented the management of a 46-year-old female with Marine-Lenhart syndrome, combining antithyroids with minimally invasive sclerotherapy to achieve euthyroidism and reduce thyroid nodule size by 58%.

In this case series, two cats with hypothyroidism and hyperthyroidism achieved clinical remission and normal thyroid function following timely diagnosis and targeted treatment with levothyroxine and methimazole, respectively.