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research Multi-ancestry tandem repeat association study of hair colour using exome-wide sequencing

February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that certain tandem repeats predict darker hair color across diverse ancestry groups and can contribute to a polygenic score for hair color, independent of SNP variation.

research Joint study of the associations of HLA‐B and the transmembrane short tandem repeat polymorphism of MICA protein with alopecia areata shows independent associations of both with the disease

7 citations , February 2020 in “Clinical and Experimental Dermatology”

This study identified an association between alopecia areata and the MICA*009 and HLA-B14 genetic markers, highlighting the importance of studying them together to better understand their role in this condition.

research Forensic DNA Phenotyping

December 2022 in “IntechOpen eBooks”

This paper discusses forensic DNA phenotyping, emphasizing its ability to infer visible traits from biological samples without reference samples, but notes ethical and legal concerns related to its use.

research Laser microdissection and DNA typing of cells from single hair follicles

45 citations , December 2004 in “Forensic Science International”

This study reports that using laser microdissection to isolate telogen hair follicles significantly improves DNA extraction efficiency for STR typing, reducing contamination from keratin.

research Pitfalls of mapping a large Turkish consanguineous family with vertical monilethrix inheritance.

4 citations , January 2009 in “PubMed”

In this study, researchers identified an autosomal dominant mutation (E402K) in exon 7 of the KRT86 gene as a cause of Monilethrix in a large family from Turkey.

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community Finasteride 1 mg,4 months progress result

in Finasteride/Dutasteride 270 upvotes 4 months ago

A user experienced positive hair growth results using 5% topical minoxidil for a year and 1 mg finasteride for four months but is considering stopping finasteride due to persistent side effects like libido loss. Others in the conversation discuss similar experiences, suggest trying topical finasteride to reduce side effects, and emphasize the importance of overall health and lifestyle.

community 2020 is here, what’s the current state for “upcoming” treatments?

74 upvotes 6 years ago

Minoxidil and finasteride are the main treatments for hair loss, with Breezula and hair cloning being explored. No definitive cure is available yet.

community Next month marks 2 years on Dutasteride. When does it start working?

in Finasteride/Dutasteride 36 upvotes 2 years ago

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

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