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research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins

2 citations, April 2018 in “Journal of Investigative Dermatology”

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

research Atrichia With Papular Lesions in a Chinese Family Caused by Novel Compound Heterozygous Mutations and Literature Review

3 citations, January 2013 in “Dermatology”

New genetic mutations causing hair loss were found in a Chinese family.

research Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing

176 citations, August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

research The Effects of 3-Hydroxy of Kaempferol on Interfollicular Epidermal Stem Cell Fate

April 2018 in “Journal of Investigative Dermatology”

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

research Impairment of Hair-Inducing Capacity of 3D-Cultured Human Dermal Papilla Cells by the Ablation of STAT5

April 2018 in “Journal of Investigative Dermatology”

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

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community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

in Finasteride/Dutasteride 26 upvotes 7 months ago

The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.