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research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine

58 citations , December 2020 in “Mayo Clinic Proceedings”

This paper discusses the variability in COVID-19 susceptibility and severity, emphasizing factors like biological differences and suggesting potential precision medicine approaches, but it reports no new clinical results.

research First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases

103 citations , January 2011 in “Blood”

This study found that thymus transplantation in infants with FOXN1 deficiency led to T-cell reconstitution and functional immunity, resolving serious infections and cytopenias.

research Regulatory T Cells: the Many Faces of Foxp3

125 citations , September 2019 in “Journal of Clinical Immunology”

This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.

research Protein-Losing Enteropathy, Anasarca and Dermatological Manifestations on People of Advanced Age: Don't Overlook the Diagnostic Hypothesis of a Cronkhite Canada Syndrome

January 2023 in “World Journal of Clinical & Medical Images”

This report discusses a late-onset case of Cronkhite-Canada syndrome that improved with prednisone treatment, highlighting the importance of early diagnosis to reduce life-threatening complications.

research A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol‐regulated transcription and the endoplasmic reticulum stress response

5 citations , October 2021 in “American Journal of Medical Genetics Part A”

This case report identifies a novel maternally inherited MBTPS2 variant associated with an expanded phenotypic spectrum of BRESHECK syndrome, including cytopenias, bone marrow fibrosis, and chronic diarrhea.

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Community Join

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community Can't get dutasteride from dermatologist office

5 upvotes 3 days ago

The user has been using oral minoxidil and finasteride for hair loss with no side effects and wants to try dutasteride but was denied by a dermatologist's office. They suspect the office was promoting Rogaine instead, which is more expensive than their current treatment.

community Don’t wait around, take action now.

452 upvotes 1 month ago

The user shared their positive experience with hair regrowth using minoxidil, finasteride, and ketoconazole shampoo, alongside lifestyle changes like a healthy diet and exercise. They emphasized the importance of starting treatment early and staying consistent.

community Don’t neglect your scalp health guys

112 upvotes 3 months ago

Improving scalp health can significantly impact hair loss treatment effectiveness. Using ketoconazole shampoo to reduce inflammation and dandruff can enhance the results of treatments like Dutasteride and Minoxidil.

community Doesn't feel like there's any good options (Rant)

in Chat 17 upvotes 4 months ago

An 18-year-old is experiencing significant hair loss and is concerned about treatment options, including finasteride, minoxidil, and dutasteride, due to potential side effects and costs. They are also taking vitamins for deficiencies and considering alternatives like hair transplants or embracing the bald look.

community Don't be inconsistent with Minoxidil, you will lose progress fast. My new plan for future.

161 upvotes 5 months ago

Inconsistent minoxidil use led to hair loss, prompting a plan to resume consistent application with derma stamping, red light therapy, and DHT blockers like clascoterone or RU58841. The user avoids finasteride and dutasteride due to past side effects.

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Learn

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learn Dutasteride

Dutasteride: Why don't some doctors prescribe it if it's stronger than finasteride? Dutasteride is off-label for hair loss in the US, the EU and the UK, stays in the body for months after the last dose, and has less long-term data in hair loss than finasteride. Its US label also states that sexual side effects may persist after stopping, with dutasteride's role unknown, and in 2026 the UK regulator added a precautionary warning about depression and suicidal thoughts.

learn Scalp Micropigmentation

Why can't I see my scalp micropigmentation after a week? Providers say fading after the first session is normal and that later sessions add density.

learn Hair Transplant

What happens if I don't have enough donor hair for a hair transplant? Body hair or beard hair can be used if scalp donor hair is insufficient.

learn Redensyl

What does Redensyl do that other natural ingredients don't? Redensyl's maker says it acts on follicle stem cells; the only human data are small supplier studies, not independent trials.

learn Baricitinib

Baricitinib: Can I use it even if I don’t have a medical diagnosis but I have patchy hair loss? Baricitinib is approved only for adults with a diagnosis of severe alopecia areata and carries an FDA boxed warning. Patchy hair loss has many causes, so doctors confirm the diagnosis before prescribing it.

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