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5 / 7 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Alopecia Areata
autoimmune disorder causing patchy hair loss
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
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Research
5 / 1000+ resultsresearch Aberrant B Cell And Cytotoxic T Cell Activation In Female Pattern Hair Loss: A Pilot Comparative Clinico-Transcriptomic Study
Immune system issues may contribute to female pattern hair loss.
research Alopecia Areata, Thyroiditis, and Vitiligo Vulgaris in a Japanese Patient with Smoldering Type Adult T-Cell Leukemia/Lymphoma
A patient with leukemia/lymphoma also had multiple autoimmune diseases, suggesting a link between them.
research Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures
The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
research Comprehensive Single-Cell Transcriptomic Profiling of the Scalp from Patients with Moderate-to-Severe Alopecia Areata
Alopecia areata involves immune system issues and specific cell types that disrupt hair growth, leading to hair loss.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
Community Join
5 / 1000+ resultscommunity Cell senescence-targeted treatment for hair loss, has anyone tried any products/enzymes etc. that use this theory
DHT causes hair loss by driving cells into senescence, and a polyphenol in black chokeberry may reverse this. A product using this theory is being considered for use alongside finasteride, minoxidil, and microneedling.
community Opinions on Scalp fibrosis and DHT?
The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.
community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.
community What are your unpopular opinions on hair loss and its treatments?
Hair loss treatments like finasteride, minoxidil, and hair transplants are more accessible and effective now. Concerns about side effects and skepticism about new treatments like hair cloning and GT20029 remain.
community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.