December 2025 in “Journal of Investigative Dermatology” Immune system issues may contribute to female pattern hair loss.
3 citations
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September 2016 in “The Journal of Dermatology” This letter to the editor discusses the occurrence of alopecia areata, thyroiditis, and vitiligo in a Japanese patient with smoldering type adult T-cell leukemia/lymphoma, but it reports no new research findings.
61 citations
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September 2010 in “Genomics” This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.
February 2026 in “Journal of Allergy and Clinical Immunology” In this single-cell transcriptomic study, researchers analyzed AA scalp samples and found distinct immune and nonimmune cell activation patterns, with elevated TH1/TH2 and JAK/STAT markers potentially contributing to hair follicle immune privilege disruption and disease severity.
November 2025 in “Scholarly Commons (Embry–Riddle Aeronautical University)” This review discusses how urban air pollutants may influence the regulation of JAK3 signaling in alopecia areata and reports no new experimental results; the authors integrate existing data to map potential pathways and biomarkers.