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research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases

6 citations , January 2023 in “International journal of molecular sciences”

This review discusses the bidirectional interactions between human mast cells and CD8 T cells in the skin, particularly in the context of disorders like psoriasis, atopic dermatitis, and vitiligo, and reports no new findings.

research 496 Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that dysregulated microRNA expression in mice may be linked to aberrant gene activity that contributes to the development of alopecia areata.

research 397 Predictive modeling of drug response and mechanism of action in alopecia areata clinical trials

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, distinct molecular mechanisms of action were identified for three drugs used in alopecia areata clinical trials, providing insights for precision medicine and treatment selection.

research Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata

55 citations , October 2015 in “Journal of Investigative Dermatology”

Alopecia areata is linked to immune-related genes, suggesting JAK inhibitors as a potential treatment.

research Diverse Role of OX40 on T Cells as a Therapeutic Target for Skin Diseases

30 citations , February 2023 in “Journal of Investigative Dermatology”

OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.

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community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 1 year ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community Why did this recent research paper from professor Tsuji lab in Japan largely go unnoticed by this sub? Isn't this discovery huge? (hair cloning)

35 upvotes 4 months ago

A recent discovery in hair cloning identified a previously unknown cell type essential for hair follicle growth, which could potentially make lab-grown hair viable if translated to humans. However, skepticism remains due to past delays and the challenges of replicating results in humans and making the process affordable.

community new way to activate stem cells to make hair grow

42 upvotes 7 years ago

Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

community Can anyone share experience with stem cell injections for hairloss?

in Chat 4 upvotes 2 years ago

Stem cell injections for hair loss are being discussed, with concerns about their effectiveness and high cost. The user is considering this treatment before opting for a hair transplant.

community Stem cell feat may lead to fix for baldness

17 upvotes 12 years ago

The conversation discusses the complexity of reversing hair loss and the need for a treatment that specifically targets DHT levels without affecting other bodily functions. It mentions finasteride as a current treatment but highlights the desire for a solution that works solely on the scalp.

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Learn

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learn Centella

Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

learn Thymosin Beta 4

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