learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
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Tracking 3 products like 13 Lonitab 10 mg, 252 Hair Solution Pyrilutamide Powder and 253 Hair Solution Pyrilutamide Powder 1g from by companies like AllDayChemist and MV supplements . View all 3 products »Learn
5 / 8 resultslearn Fluridil
a topical anti-androgen with less systemic involvement
learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
Research
5 / 1000+ results
research Simultaneous Effects of Tocopheryl Polyethylene Glycol Succinate on Local Hair Growth Promotion and Systemic Absorption of Topically Applied Minoxidil in a Mouse Model
Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.
research Systemic Effects of Leucaena Leucocephala Ingestion on Ringtailed Lemurs (Lemur Catta) at Berenty Reserve, Madagascar
Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.
research Lack of Endocrine Systemic Side Effects After Topical Application of Spironolactone in Men
Topical spironolactone cream doesn't cause hormone-related side effects in the body.
research Quality of Life, Burden of Disease, Comorbidities, and Systemic Effects in Vitiligo Patients
Vitiligo affects overall health and self-esteem, needing more research and awareness.
research Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
Community Join
5 / 1000+ resultscommunity Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?
The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.
community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
community oral minoxidil collagen contradiction
The conversation discusses concerns about oral minoxidil potentially aging the face by affecting collagen, questioning its systemic effects. The user has successfully used topical minoxidil for years and is hesitant to switch to oral minoxidil.
community Is there any new drug that looks promising ?
The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.
community A Nuanced Look at Microdosing Topical Finasteride
The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.