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In this study, researchers explored the effects of various medications on eye health, noting that systemic and local ophthalmic drugs can lead to both widespread and specific ocular side effects, with serious adverse events most associated with neurotropic, immunotropic, and antitumor medications.

JAK inhibitors are effective and generally safe for treating alopecia areata, but monitoring for side effects is important.

This retrospective study found a variety of dermatological adverse events associated with antineoplastic treatments, often leading to changes or suspension of cancer therapies in affected patients.

This study found that topical patidegib gel significantly shrank basal cell carcinomas in Gorlin syndrome patients without causing the systemic side effects common with oral hedgehog inhibitors.

This review synthesizes information on isotretinoin’s systemic toxicity, emphasizing that its adverse effects, including mucocutaneous, hepatic, and musculoskeletal reactions, primarily reflect its pharmacodynamic actions and are generally manageable with individualized dosing and monitoring, though its teratogenicity remains a significant safety concern.