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research Is sulfonamide group of tamsulosin main factor in the pathophysiology of floppy iris syndrome?

January 2018 in “Haydarpaşa Numune Hastanesi tıp dergisi”

This study hypothesizes that the sulfonamide group in tamsulosin might contribute to its association with intraoperative floppy iris syndrome.

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs

26 citations , July 2007 in “Biochemical Pharmacology”

This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.

research Circumventing Mukaiyama oxidation: selective S–O bond formation via sulfenamide–alcohol coupling

January 2026 in “Beilstein Journal of Organic Chemistry”

This study developed a metal-free method for synthesizing sulfinimidate esters, showcasing their potential as versatile intermediates for enantioselective bond formation under mild conditions.

research Toxic Epidermal Necrolysis

74 citations , September 1980 in “Medical Clinics of North America”

This article discusses toxic epidermal necrolysis, highlighting its high mortality rate despite aggressive treatment, and notes controversy over using high-dose systemic corticosteroids as therapy.