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research Global Adiposity Rather Than Abnormal Regional Fat Distribution Characterizes Women with Polycystic Ovary Syndrome

149 citations , December 2007 in “The Journal of Clinical Endocrinology and Metabolism”

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

research Current concepts in aesthetic endocrinology

15 citations , January 2002 in “Gynecological endocrinology”

This review discusses the extragenital effects of ovarian steroids, particularly focusing on aesthetic endocrinology, which suggests estrogens may slow skin aging post-menopause, though hair loss treatment efficacy is mainly confirmed for minoxidil.

research Current concepts in aesthetic endocrinology

4 citations , December 2002 in “Gynecological Endocrinology”

This review discusses the role of ovarian steroids in skin and hair metabolism, and suggests estrogens could slow skin aging post-menopause, while minoxidil is effective for women's hair loss.

research Treatment of Lipodystrophy with Troglitazone

1 citations , June 2001 in “Annals of Internal Medicine”

This letter to the editor discusses data from a study on troglitazone for lipodystrophy, noting significant increases in subcutaneous fat without dietary changes.

research Abdominal Fat Quantity and Distribution in Women with Polycystic Ovary Syndrome and Extent of Its Relation to Insulin Resistance

270 citations , April 2007 in “The Journal of Clinical Endocrinology and Metabolism”

This study found that PCOS patients had higher amounts of central abdominal fat compared to weight-matched controls, which was associated with increased insulin resistance.

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community Subcutaneous Scalp fat and Hair loss? Interested in others annecdotal experience or knowledge.

6 upvotes 3 years ago

Subcutaneous scalp fat may be linked to hair loss, with theories suggesting that fat loss can lead to reduced blood flow and increased DHT activity, contributing to hair loss. Treatments discussed include PRP/PRF injections and fat transfer to improve scalp thickness and blood flow.

community MPB is correlated with excess epicardial fat

202 upvotes 1 week ago

Hair loss is linked to excess epicardial fat, which may affect blood flow to hair follicles. Treatments mentioned include minoxidil, finasteride, and dutasteride.

community My Estradiol Level on Finasteride

18 upvotes 1 year ago

Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

110 upvotes 2 years ago

Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

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