55 citations
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July 1999 in “Clinics in Sports Medicine” This review discusses recent data on the use of anabolic-androgenic steroids and other steroid compounds and reports no new clinical results.
December 2023 in “Biointerface Research in Applied Chemistry” This study used molecular docking to identify stiripentol as a potential new inhibitor of the SRD5A2 enzyme, which is targeted for treating androgen-related diseases; however, in vivo trials are needed to validate its efficacy.
2 citations
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January 2006 in “Durham e-Theses (Durham University)” This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.
5 citations
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January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry” This study found that certain steroidal compounds, especially 10a–10c, demonstrated strong antiandrogenic activity by binding to the androgen receptor and reducing prostate weight in a hamster model.
2 citations
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January 2022 in “Rasayan journal of Chemistry” This study analyzed the affinity, stability, and pharmacokinetics of compounds from Sansevieria trifasciata, reporting that three compounds showed promising molecular docking results against the androgen receptor and satisfactory pharmacokinetic profiles, similar to minoxidil, in an in-silico setting.