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Glossary Steroid Cell Tumor

rare ovarian tumor producing excess steroids, causing hormonal issues

A Steroid Cell Tumor is a rare type of ovarian tumor that originates from cells capable of producing steroids, such as testosterone or cortisol. These tumors can lead to hormonal imbalances, causing symptoms like excessive hair growth (hirsutism) or menstrual irregularities. They are typically benign but can sometimes be malignant, requiring careful medical evaluation and treatment.

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Research

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research Steroid Cell Tumours: Rare Ovarian Tumours that Cause Hyperandrogenaemia in Postmenopausal Women

December 2020 in “Research Square (Research Square)”

This case series detailed three postmenopausal women with ovarian steroid cell tumors, highlighting that such tumors may present asymptomatically or with virilization, and found surgery effectively normalized androgen levels, with distinctive imaging features aiding diagnosis.

research Single-cell transcriptome analysis in ovarian steroid cell tumors-not otherwise specified

July 2026 in “Journal of Ovarian Research”

In this study, researchers used single-cell RNA sequencing to identify seven cell types, including distinct steroidogenic and immune cells, in the tumor microenvironment of a case of ovarian SCT-NOS, providing insights into its cellular heterogeneity and molecular mechanisms related to hyperandrogenism.

research Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review

65 citations , April 2018 in “Oncotarget”

This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.

research A Virilizing Malignant Steroid Cell Tumor-Leydig Cell Subtype in a 24-Year-Old Palestinian Female with Challenging Histopathological and Biochemical Features: A Case Report

April 2023 in “Research Square (Research Square)”

This case study of a young Palestinian woman illustrates the diagnostic and treatment challenges of ovarian steroid cell tumors, highlighting the importance of detailed examination when hormonal therapy fails.

research Sertoli–Leydig cell tumors: hormonal profile after dynamic test with GnRH analogue: triptorelin represents a useful tool to evaluate tumoral hyperandrogenism

5 citations , October 2014 in “Gynecological Endocrinology”

This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.

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Community Join

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community Expectations control for SCUBE3

20 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community is the reason why people are in denial about prolactin causing hair loss is the fact that prolactin is one of the hardest things to lower?

21 upvotes 2 years ago

High prolactin levels can cause hair loss, and finasteride may increase prolactin. Cabergoline or Vitamin B6 might lower prolactin, but combining them with finasteride requires caution.

community If PP405 works it will be fkn impossible to buy it.

103 upvotes 10 months ago

PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

community Stem cell feat may lead to fix for baldness

17 upvotes 12 years ago

The conversation discusses the complexity of reversing hair loss and the need for a treatment that specifically targets DHT levels without affecting other bodily functions. It mentions finasteride as a current treatment but highlights the desire for a solution that works solely on the scalp.

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