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    Did you mean Spironolactone?
    Glossary Spironolactone

    medication that blocks hormones to treat hair loss and acne

    Spironolactone, also known by the brand name Aldactone, is a medication primarily used as a diuretic and antihypertensive. It works by blocking the action of aldosterone, a hormone that regulates salt and water balance in the body. In addition to its primary uses, it is also prescribed off-label for conditions like acne and hirsutism (excessive hair growth) due to its anti-androgenic properties, and it can be beneficial in treating certain types of hair loss, such as androgenetic alopecia.

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    1. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
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    Research 10 of 1000+

    1. Lack of effect of spironolactone on hair shaft diameter in hirsute females Postgraduate medical journal · 1989 · 23 citations
    2. Spironolactone and XPB: An Old Drug with a New Molecular Target Biomolecules · 2020 · 18 citations
    3. Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing International Journal of Pharmaceutics · 2021 · 9 citations
    4. Case report: A pregnant woman accidental treated with spironolactone in mid-gestation Frontiers in Pharmacology · 2024 · 1 citations
    5. The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review Clinical, Cosmetic and Investigational Dermatology · 2023
    6. Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review American Journal of Clinical Dermatology · 2017 · 117 citations
    7. Treatment of Hirsutism With Spironolactone JAMA · 1982 · 183 citations
    8. Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial Fertility and Sterility · 1994 · 165 citations
    9. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women Fertility and sterility · 1985 · 142 citations
    10. A Novel Use of Spironolactone: Treatment of Hirsutism 1980 · 124 citations
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    Community 10 of 255

    1. Anyone here used spirolactone/cyproterone acetate/bicalutamide? Reddit · 8 Sept 2025
    2. Doctor prescribed me Spironolactone instead of Finasteride Reddit · 15 Sept 2026
    3. If i add a little daily dose of spironolactone (25 mg a day) would the improvement to my hair loss be significant? and also how likely is it to give me unwanted effects? My current regimen is 6 days / week oral Finasteride, 1 day / week oral Dutasteride and twice a day minoxidil foam Reddit · 29 Aug 2026
    4. Any men here taking oral spironolactone? Reddit · 16 Jul 2026
    5. I am a 30 yo woman and having been taking oral minoxidil and spirinolactone... nothing. What gives? Reddit · 24 Apr 2026
    6. Why is nobody talking about topical Spironolactone? Reddit · 10 Apr 2026
    7. Dose of oral spironolactone for males to stop hairloss when 5ari blockers not working, any idea Reddit · 5 Apr 2026
    8. spironolactone vs dutasteride Which one is more effective? Reddit · 24 Mar 2026
    9. What combination should I do of min, fin and spironolactone - woman Reddit · 16 Jan 2026
    10. Are there any males here that use (or have used) topical spironolactone? Reddit · 2 Jan 2026
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