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GlossaryKennedy's Disease (Spinal and Bulbar Muscular Atrophy)

x-linked genetic disorder causing muscle weakness and atrophy

Kennedy's Disease, also known as Spinal and Bulbar Muscular Atrophy (SBMA), is a rare, X-linked genetic disorder that primarily affects males. It is characterized by the progressive degeneration of motor neurons in the spinal cord and brainstem, leading to muscle weakness, atrophy, and sometimes endocrine disturbances such as gynecomastia and reduced fertility.

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research Valproate, Acetylcarnitine, Folic Acid, and Vitamin B12 in Spinal Muscular Atrophy: Preliminary Data of an Open-Label Study in Children

1 citations, September 2007 in “Neuromuscular disorders”

The treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may improve muscle strength in children with SMA without significant side effects.

research Spinal and Bulbar Muscular Atrophy: Pathogenesis and Clinical Management

42 citations, May 2013 in “Oral Diseases”

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?

17 citations, July 2017 in “Molecular and Cellular Endocrinology”

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients

48 citations, June 2014 in “Neurobiology of Disease”

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

research Agent-Specific Effects of Anticoagulant-Induced Alopecia

7 citations, May 2017 in “Research and Practice in Thrombosis and Haemostasis”

Some blood thinners can cause hair loss, but switching medications can stop it.

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in Research/Science 22 upvotes 3 years ago

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in Research/Science 128 upvotes 3 years ago

Many people experience hair loss but don't treat it. Common treatments include Minoxidil, Finasteride, and microneedling.

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