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      learn Finasteride

      Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Pyrilutamide

      • Can pyrilutamide be used by both men and women, or only in specific cases? Pyrilutamide (KX-826) is an investigational topical anti-androgen that has been trialled in men and women but is not approved for hair loss anywhere. Its sponsor reports one failed (2023) and one successful (2026) Phase III in men, none of it peer-reviewed; long-term safety is unknown, and anti-androgens are not considered appropriate in pregnancy.