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research The “spade sign” as a pathognomonic histopathologic feature of acne keloidalis: Analysis of 33 cases of cicatricial alopecia

June 2021 in “Journal of The American Academy of Dermatology”

This study suggests that the "spade sign" is a highly specific histopathologic feature of acne keloidalis, although its absence does not rule out the condition.

research SPACE-Peptide succesfully improves dermis penetration of amniotic membrane stem cell metabolite product as antiaging

August 2026 in “JURNAL ILMU KEFARMASIAN INDONESIA”

This study found that the addition of SPACE peptide significantly enhanced the penetration of amniotic membrane stem cell metabolites in mice, with only very mild irritation observed.

research The ‘Watch Sign’ – Another Observation in the Course of Male Frontal Fibrosing Alopecia

1 citations , April 2024 in “Dermatology Practical & Conceptual”

Hair loss in male frontal fibrosing alopecia may spare areas covered by a wristwatch.

research Plant responses to shade

1 citations , September 1984 in “Journal of Biological Education”

Plants change their growth in response to shade based on light signals detected by phytochrome.

research Modeling cell–cell communication for immune systems across space and time

20 citations , November 2019 in “Current Opinion in Systems Biology”

This review discusses how recent studies use models and experiments to understand immune system signaling, but it reports no new clinical findings; the authors suggest strategies for improving these models.

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Community Join

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community No sign of improvement after one year on Fin 1mg daily

92 upvotes 4 months ago

Finasteride is used to prevent further hair loss, not for regrowth. Adding minoxidil is suggested for potential hair regrowth.

community Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway

53 upvotes 8 years ago

A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.

community Hair not shedding but thinning on dut? Not a good sign imo.

48 upvotes 1 year ago

The conversation is about a user concerned about hair thinning despite using finasteride, minoxidil, RU58841, and recently adding dutasteride. Most responses suggest there is no noticeable difference in hair loss, attributing concerns to paranoia, and recommend continuing the current treatment or adjusting expectations.

community Hair loss over a year following depression and taking antidepressants

in Side effects? 200 upvotes 8 months ago

A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

community The PP405 news are the best news we've had in the last 20 or more years.

599 upvotes 1 year ago

PP405 significantly improves hair density, outperforming finasteride, with 31% of users seeing over 20% improvement in four weeks. Concerns exist about its availability, cost, and long-term effects.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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