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Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

66 citations, July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

research Effects of Guasha on Histomorphology of Scraped Skin and Expression of Calcitonin Gene-Related Peptide and Substance P in Rats

3 citations, August 2018 in “Deleted Journal”

Guasha changed rat skin appearance and blood vessels temporarily without affecting certain nerve proteins or fiber structure.

research Mast Cell Deficient and Neurokinin-1 Receptor Knockout Mice Are Protected from Stress-Induced Hair Growth Inhibition

76 citations, March 2005 in “Journal of Molecular Medicine”

Certain mice without specific receptors or mast cells don't lose hair from stress.

Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways

research Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways

194 citations, March 2003 in “American Journal of Pathology”

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

research Alopecia Areata: A Review of Disease Pathogenesis

191 citations, May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

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Community Join

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community Just got my first perm fellas.

in Progress Pictures 205 upvotes 9 months ago

The conversation is about a user who got a perm after successfully treating their thinning hair, with mixed reactions from others on the appearance. Specific treatments used are not mentioned.

community Just had this wild thought come into my head.

in Satire 403 upvotes 8 months ago

The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

in Finasteride/Dutasteride 14 upvotes 1 year ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

community thoughts on topical Saw Palmetto oil

in Treatment 4 upvotes 5 months ago

The user is considering topical Saw Palmetto or Pumpkin Seed Oil due to sensitivity to finasteride and cost issues. They also use dermastamping for Minoxidil absorption and seek advice on timing to avoid systemic absorption.

community I attempted to explain why Saw Palmetto is BS, now I think taking it with Fin isn't a bad idea.

in Finasteride 6 upvotes 6 years ago

Saw Palmetto may act like a weaker version of finasteride and could be too weak to treat male pattern baldness (MPB) on its own. However, combining Saw Palmetto with low doses of finasteride might increase effectiveness with less risk of prostate shrinkage and sexual side effects.

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