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4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

research 4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

5 citations , February 2017 in “Biomolecules & Therapeutics”

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

research Cooperation of TGF-β and FGF Signalling Pathways in Skin Development

23 citations , May 2023 in “Cell Proliferation”

TGF-β and FGF pathways are crucial for skin development and regeneration.

research Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients

March 2023

Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.

research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

245 citations , January 2018 in “Bone Research”

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

research Transforming Growth Factor-β, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

16 citations , February 2007 in “Plastic and Reconstructive Surgery”

Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.

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Community Join

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community Creatine Does Not Increase DHT And Does Not Cause Hair Loss - Randomized Controlled Trial

in Research/Science 307 upvotes 7 months ago

Creatine does not increase DHT levels or cause hair loss. Personal experiences vary, but scientific evidence shows no link between creatine and hair loss.

community My Theory Of Androgenic Alopecia

in Research/Science 17 upvotes 1 week ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 380 upvotes 1 year ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Creatine's effect on Hair Loss and DHT

in Research/Science 100 upvotes 1 year ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community Minox and fin since start of January 2020, also shaved my head twice since then to get full effects of the minoxidil and reach the whole scalp easier, that’s honestly a huge key

in Progress Pictures 234 upvotes 4 years ago

User experienced significant hair regrowth using Minoxidil and Finasteride since January 2020, with no side effects reported. Shaving head twice helped Minoxidil reach scalp more effectively.

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