6 citations
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September 2012 in “Clinical Interventions in Aging” This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.
January 2026 in “Microsystems & Nanoengineering” This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.
1 citations
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June 2016 in “Yāftah/hā-yi nuvīn dar ̒ulūm-i zīstī” This study found that sheep testis extract significantly improved wound healing and hair follicle growth in rats, suggesting it may be a promising candidate for clinical wound healing research.
June 2026 in “Scientific Reports” This study found that systemic testosterone exposure in transgender individuals with XX genotype alters skin biology, increasing androgen and estrogen receptor-positive cells, collagen density, and fibronectin expression while reducing immune cells, which could affect surgical outcomes by promoting a male skin phenotype.
14 citations
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November 1982 in “British Journal of Dermatology” This article discusses whether testosterone's metabolism to 5α-dihydrotestosterone is necessary for androgenic effects in the skin but reports no new experimental results.