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research Sex hormone supplementation improves breathing and restores respiratory neuroplasticity following C2 hemisection in rats

3 citations , May 2024 in “Frontiers in Physiology”

In this study, male rats with spinal cord injury that received either E2 or DHT supplementation both showed restored expression of respiratory neuroplasticity following acute intermittent hypoxia, with E2 also enhancing overall breathing recovery.

research Sex Hormones and Frailty in Older Men: The Osteoporotic Fractures in Men (MrOS) Study

January 2010 in “Yearbook of Endocrinology”

Older men with lower levels of available testosterone are more likely to be frail.

research Sex Hormones and Related Compounds, Including Hormonal Contraceptives

1 citations , January 2014 in “Side effects of drugs annual”

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

research Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial

2 citations , November 2025 in “Nutrition Journal”

This study found that an 8-week supplementation with specific probiotic strains improved hormonal markers and oxidative stress while decreasing inflammation in women with PCOS, although clinical symptoms like acne and hirsutism showed no significant improvement compared to the placebo group.

research Effects of supplementation with two probiotic strains on metabolic profile, hormonal status, oxidative stress, and quality of life in women with polycystic ovary syndrome: A study protocol for a randomized clinical trial

January 2026 in “International Journal of Reproductive BioMedicine (IJRM)”

The hypothesis in this study is that probiotic supplementation could improve hormonal, metabolic, inflammatory, and antioxidant markers in individuals with PCOS compared to a placebo, although results are not yet reported.

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Community Join

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community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 year ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

community Vitamins Deficiency and blood works result

in Treatment 2 upvotes 1 year ago

The conversation is about a user planning to start minoxidil treatment and considering increasing zinc intake to improve testosterone and libido. They are concerned about potential hair loss due to increased testosterone and are advised to consider magnesium supplementation and the effects of DHT if not on finasteride or dutasteride.

community Thoughts on Pre-Finasteride Bloodwork? Normal/high Total and Free Testosterone, Low DHEA-S?

5 upvotes 4 years ago

A 23-year-old male is considering starting Finasteride for hair loss after experiencing persistent shedding and hairline recession, with bloodwork showing normal testosterone levels but low DHEA-S and Vitamin D. He plans to discuss DHEA supplementation with his doctor and has already started Vitamin D supplementation.

community Is Cialis the best option for when you have ED on DHT blockers?

in Chat 61 upvotes 2 months ago

The conversation discusses using finasteride for hair loss and its side effect of erectile dysfunction (ED), with some users suggesting reducing the dose to 0.5mg to minimize side effects. Cialis is recommended for managing ED, and other suggestions include monitoring hormone levels and considering supplements like DIM or L-Citrulline.

community Libido on Finasteride

4 upvotes 11 years ago

The conversation discusses the effects of finasteride on libido, with the original poster experiencing a significant decrease in sexual desire after starting the medication. Other users share similar experiences and suggest potential remedies, including Vitamin E supplementation and lifestyle changes like avoiding pornography.

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Learn

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learn Biotin

B vitamin, often sold as a hair supplement

learn dehydroepiandrosterone

learn Tribulus terrestris extract

learn Clascoterone

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

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Clinics

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