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research Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones

197 citations , January 2019 in “Neuropsychopharmacology”

This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.

research Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone

168 citations , January 2005 in “Journal of Investigative Dermatology”

Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.

research Sex differences in COVID-19: the role of androgens in disease severity and progression

121 citations , November 2020 in “Endocrine”

This review discusses evidence on androgen sensitivity as a potential factor in COVID-19 disease severity, suggesting that androgen receptor interactions could influence virus entry and progression, and reports no new clinical results.

research Sex differences in SARS-CoV-2 infection rates and the potential link to prostate cancer

113 citations , July 2020 in “Communications biology”

This review suggests that understanding the biological and molecular reasons for more severe COVID-19 in men, particularly those at risk for prostate cancer, could improve management of these patients, but reports no new results.

research Sex differences in arterial hypertension

47 citations , September 2022 in “European Heart Journal”

This consensus document reviews current knowledge on sex differences in essential hypertension and identifies areas needing further research to improve sex-specific prevention and management strategies.

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Community Join

5 / 824 results

community 0.25mg Fin every day, 2 months status report

9 upvotes 4 years ago

A user reported increased shedding and some side effects like ball ache and potential watery semen after taking 0.25mg of finasteride daily for two months, but noted a high sex drive and considered the shedding a possible sign of new hair growth. Other users discussed dosage differences, with some suggesting starting with a smaller dose and monitoring effects, while others shared their experiences with no shedding or hair growth yet.

community Fix/min after 9 months - can you spot the difference?

in Is this regrowth? 141 upvotes 8 months ago

The user experienced significant hair regrowth after using minoxidil for 9 months and finasteride for 3 months, with plans to continue treatment and possibly get a hair transplant. Some users suggested adding microneedling and other treatments, while others discussed potential side effects of finasteride.

community One month difference between pictures

in Progress Pictures 330 upvotes 1 year ago

The user is using oral minoxidil, finasteride, and biotin for hair loss, with positive results after two months. They have also improved their diet and exercise routine, and report no side effects from the medication.

community 2 months of difference with estradiol and spiro (4 months total w/ estradiol & spiro; 4 years of minoxidil and finasteride) (you should not take estradiol or spiro if you look manly and want to continue looking manly)

122 upvotes 1 year ago

Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hair loss due to feminizing effects.

community Have you noticed any difference in mood or energy since being on fin/dut?

in Finasteride/Dutasteride 25 upvotes 3 years ago

Users discuss effects of Finasteride/Dutasteride on mood and energy. Some experience depression, focus issues, and libido changes.

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Learn

2 / 801 results

learn Melatonin

Melatonin: Does it work the same for men and women? No trial has compared melatonin's effect on hair in men versus women. The only placebo-controlled scalp study enrolled 40 women, and the single reported sex difference — shedding fell in women but not men — comes from one uncontrolled 60-person observation, so any difference is unestablished.

learn Overview

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Clinics

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Experts

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