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Research

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research Treating Scars: Addressing Surface, Volume, and Movement to Expedite Optimal Results. Part 2: More-Severe Grades of Scarring

13 citations , June 2012 in “Dermatologic Surgery”

This review discusses treatment strategies for managing scarring based on severity using volume, surface, and movement interventions, but does not present new experimental results.

research Severe scarring alopecia associated with combinational use of ficlatuzumab and gefitinib: a clinical and immunohistochemistry study

1 citations , December 2012 in “Journal of dermatological science”

This study introduces ficlatuzumab, an anti-HGF monoclonal antibody, in combination with gefitinib in a phase 2 trial to address EGFR TKI resistance in Asian NSCLC patients.

research Severe Refractory Scarring Alopecia Associated With Combinational Use of Ficlatuzumab (AV-299) and Gefitinib

6 citations , May 2013 in “Journal of Clinical Oncology”

Combining Ficlatuzumab and Gefitinib can cause severe hair loss.

research Severe diffuse non-scarring hair loss in systemic lupus erythematosus - clinical and histopathological analysis of four cases

15 citations , December 2011 in “Journal of the European Academy of Dermatology and Venereology”

In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.

research Severe Psoriasis Leading to Scarring Alopecia of the Scalp Responding to Biologic Therapy

May 2026 in “SKIN The Journal of Cutaneous Medicine”

This case report presents the first known instance of bimekizumab improving psoriatic scarring alopecia, suggesting potential benefits of dual IL-17A/IL-17F blockade for this rare and challenging condition, warranting further investigation.

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Community Join

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community I wasn't expecting this while using topical finasteride aka fincrezo for Europe(France)

1 upvotes 2 months ago

Topical finasteride unexpectedly cleared the user's severe facial acne, which they attribute to reduced DHT levels. Another user shared a similar experience with topical minoxidil and oral finasteride, noting reduced acne and scarring.

community Trying to understand severe shedding and progressive density loss after a successful hair transplant

8 upvotes 4 weeks ago

The user is experiencing severe shedding and progressive hair density loss after a successful hair transplant, despite using finasteride, minoxidil, microneedling, and scalp treatments. Suggestions include trying stronger treatments like oral dutasteride, topical RU58841, and higher doses of oral minoxidil.

community Advice for woman that doesn't have recession; just trying to make my natural "M" widow's peak into an upside down "U" if that makes sense? Minimal scarring with maximum density. Prefer long hair transplant if possible. Big discussion of techniques and surgeons inside.

1 upvotes 1 year ago

The user is seeking advice on hair transplant techniques and surgeons to reshape a natural widow's peak into a more rounded hairline, preferring long hair transplants with minimal scarring and maximum density. They are currently using finasteride and oral minoxidil, which have not been effective, and are considering various surgeons primarily in English-speaking countries and the EU, excluding Turkey.

community Terrible scalp itch and hair loss

16 upvotes 3 years ago

Severe scalp itching and hair loss, possibly linked to seborrheic dermatitis, are discussed, with treatments like Dutasteride, Finasteride, and various shampoos mentioned. Some users find relief from itching with DHT blockers like Finasteride, while others suggest consulting multiple dermatologists for accurate diagnosis.

community Insane shed 3 months on Fin + Min Oral

88 upvotes 4 months ago

The user experienced severe hair shedding after starting oral Minoxidil and Finasteride, possibly due to stress from a breakup. Many suggest the shedding resembles alopecia areata and recommend seeing a doctor immediately.

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Learn

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learn Scalp Micropigmentation

Can scalp micropigmentation hide my scars? Providers say SMP can make scalp scars much less visible, but not invisible; this is a provider claim, not a measured result.
What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Exosomes

What are exosomes and how do they help regenerate hair in cases of severe hair loss? Exosomes are cell-derived vesicles that some clinics promote for hair regrowth. No exosome product is FDA-approved, and human evidence is limited to small, uncontrolled reports.

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