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research Proliferation and Differentiation of Cultured Human Keratinocytes is Modulated by 1,25(OH)₂D₃ and Synthetic Vitamin D₃ Analogues in a Cell Density‐, Calcium‐ and Serum‐Dependent Manner*

39 citations , January 1997 in “Pharmacology & toxicology”

This study found that human keratinocytes' sensitivity and response to vitamin D3 analogues vary based on cell density, serum availability, and calcium concentration.

research Development of Suspended Droplet Microextraction Method for Spectrophotometric Determination of Serum Iron

1 citations , May 2025 in “Analytical Science Advances”

This study presented a new method for accurately measuring Fe³⁺ in small serum samples, achieving high recovery rates and agreement with established testing methods, while offering advantages such as cost-effectiveness, simplicity, and enhanced sensitivity.

research The prevalence of thyroid function test abnormalities and serum thyroid autoantibodies in vitiligo and alopecia areata patients in Saudi Arabian population

February 2024 in “International Journal of Research in Dermatology”

In this study, researchers examined thyroid function and autoantibody levels in patients with alopecia areata and vitiligo, finding similar rates of thyroid dysfunction and autoantibody presence in both groups, with no significant differences based on ethnicity or gender.

research - Global bibliometric analysis of nanoemulsion-based serums for hair growth (2015-2025): Trends, collaborations, and future directions

June 2026 in “Journal of Pakistan Association of Dermatologists”

This study reported that the development of nanoemulsion-based hair growth serums is increasing, with enhanced international collaboration and scientific presence, especially between China and the United States.

research Periocular nasociliary lesion with elevated serum IgG4 levels: A case report on the risks of overdiagnosis in IgG4-related disease

July 2026 in “World Journal of Advanced Research and Reviews”

In this report, an 80-year-old male with elevated serum IgG4 presented with a lesion suggestive of IgG4-related ophthalmic disease, but lack of orbital imaging and biopsy precluded definitive diagnosis, highlighting the necessity of excluding similar conditions before long-term treatment.

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Community Join

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community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 598 upvotes 1 year ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

community Research Backed Dutasteride Simulator (Serum/Scalp DHT included for all doses)

116 upvotes 1 year ago

A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.

community 📈 Solving for very low dose topical finasteride titration intervals

in Research/Science 30 upvotes 2 years ago

The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.

community If I would have started earlier I would probably have quit

in Chat 117 upvotes 1 year ago

The conversation discusses hair loss treatments, including Avodart (Dutasteride), finasteride, minoxidil, and peptide serums with ingredients like Redensyl and Saw Palmetto. Users share experiences and opinions on the effectiveness and side effects of these treatments, with some skepticism about claims regarding DHT and its role in hair loss.

community How essential is scalp biopsy when dealing with hair loss?

in Treatment 6 upvotes 1 year ago

The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

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Learn

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learn Hyaluronic Acid

What’s the difference between using hyaluronic acid as a serum on the scalp versus taking it as a supplement? A serum sits on the scalp surface. Oral hyaluronic acid has small trials on facial wrinkles, none on the scalp or hair.

learn Baicapil

Could a daily serum with Baicapil help revive dormant hair follicles before it’s too late? There is no independent evidence that Baicapil revives dormant follicles; the only human data are the supplier's own unpublished test. A dermatologist can tell whether follicles are still active and which treatments have evidence.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is FDA-approved only for eyelashes, not the scalp. In the larger of two Allergan phase 2 scalp trials, every bimatoprost formulation gave smaller hair-count gains than minoxidil 5%; the results were posted to ClinicalTrials.gov but never published in a journal, and scalp use remains off-label and experimental.

learn Exosomes

Are exosomes applied as a serum, an injection, or combined with other hair treatments? Clinics offer exosomes as scalp injections, as serums applied after microneedling, or combined with PRP. No exosome product is FDA-approved, and no reliable evidence shows that any of these methods works.

learn Omega 3

Can topical omega-3 oils or serums nourish the scalp, and is taking omega-3 by mouth any better? There is little evidence that omega-3 helps hair, whether taken by mouth or applied to the scalp.

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Clinics

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Hair Loss Treatments
Clínica SerumMérida, Yucatán · MX

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