48 citations
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April 2023 in “Aging Cell” This review discusses cellular senescence in human skin, detailing both beneficial and detrimental effects and suggesting the potential for therapies targeting senescence-related skin disorders, but reports no new clinical results.
3 citations
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March 2023 in “Life” This review discusses recent findings on wound healing with a focus on adipose tissue biology and obesity, but presents no new clinical results.
April 2018 in “Journal of Investigative Dermatology” This study found that inhibiting NF-κB Essential Modulator (NEMO) in senescent murine dermal fibroblasts successfully reduced key factors associated with the senescence associated secretory phenotype (SASP), highlighting its potential as a therapeutic target for aging-related diseases.
July 2014 in “European Journal of Cancer” p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.
27 citations
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July 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.