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research Follicular transport route – Research progress and future perspectives

211 citations , February 2009 in “European journal of pharmaceutics and biopharmaceutics”

This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.

research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products

188 citations , October 2012 in “The AAPS Journal”

This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.

research Promoting of Biomechanics' Properties Incisional Wound Repair by Mesenchymal Stem Cell Transplantation.

January 2025 in “PubMed”

This study found that stem cells from semi-solid bone marrow improved healing in diabetic incision wounds by enhancing epidermal thickness and blood vessel growth.

Evaluation of Caffeine Liberation from Dermal Semisolid Drugs

research [Evaluation of liberation of caffeine from dermal semisolids drugs].

October 2013 in “PubMed”

This study determined that the optimal formulation for caffeine-based hydrogels involves 0.2% caffeine and 2.3% chitosan, based on gel liberation and stability testing.

research Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact

62 citations , October 2010 in “Journal of biomedical nanotechnology”

This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.

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Community Join

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community PSA: If you're prone to MPB dont take creatine

103 upvotes 3 years ago

Creatine might speed up hair loss in those prone to male pattern baldness, possibly due to increased DHT levels. Some users experience no issues when using creatine with treatments like finasteride, minoxidil, or dutasteride.

community 3,5 months of only topical minoxidil

776 upvotes 9 months ago

A 24-year-old reported new hair growth on temples after 3.5 months of using topical minoxidil without shedding. They plan to add finasteride to maintain progress, as minoxidil alone may not be enough long-term.

community Dont stop using Minoxidil i beg you! Dont be fool like me.

in Minoxidil 507 upvotes 1 year ago

Stopping minoxidil causes significant hair loss, as continued use is necessary for maintaining gains. Combining minoxidil with finasteride may help maintain hair, but both treatments are typically lifelong commitments.

community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

494 upvotes 10 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

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