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Immunohistochemical Analysis of Estrogen and Progesterone Receptors in Endometrium and Peritoneal Endometriosis: A New Quantitative Method

research Immunohistochemical Analysis of Estrogen and Progesterone Receptors in Endometrium and Peritoneal Endometriosis: A New Quantitative Method

June 1995 in “International Journal of Gynecology & Obstetrics”

The new method showed that endometriotic tissue has lower estrogen receptor levels but similar progesterone levels compared to normal endometrium, with both following a similar cycle.

research Overexpression of IL-18 in the Proliferative Phase Endometrium of Patients With Polycystic Ovary Syndrome

21 citations, June 2016 in “Reproductive Sciences”

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

research A Missing Piece: The Spiny Mouse And The Puzzle Of Menstruating Species

24 citations, May 2018 in “Journal of Molecular Endocrinology”

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

research Angiogenin Is Expressed in Human Dermal Papilla Cells and Stimulates Hair Growth

20 citations, October 2008 in “Archives of dermatological research”

Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.

Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy

research Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy

January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu”

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

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community My Dad seems to get his hair back?

in Question 19 upvotes 6 years ago

A user's father, mostly bald for 20 years, is regrowing hair using a serum called "Skrzypovita Serum Pro" without minoxidil. The user is curious about which ingredients might be causing hair growth.

community New Hair Loss Treatment: Adipose Derived Secretomes

in Research/Science 16 upvotes 1 month ago

Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

in Research/Science 44 upvotes 4 months ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community Clascoterone (Winlevi) now approved in Canada

in Product 14 upvotes 1 year ago

The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

community Wouldn’t it be funny if there already was a drug that existed which reactivated sleeping follicles? It would be our own version of Ozempic

in Research/Science 204 upvotes 5 months ago

PP405 shows promise for reactivating hair follicles, with potential maintenance using 5AR inhibitors. Current treatments like Minoxidil and finasteride are effective but have limitations, and there is hope for more effective solutions in the future.

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