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    Did you mean Secreted Frizzled-Related Protein 2?
    GlossarySecreted Frizzled-Related Protein 2

    regulates cell signaling pathways affecting hair follicle development

    Secreted Frizzled-Related Protein 2 (SFRP2) is a protein that plays a role in regulating cell signaling pathways, particularly the Wnt signaling pathway, which is crucial for cell growth, differentiation, and development. In the context of hair biology, SFRP2 can influence hair follicle development and cycling, potentially impacting conditions like alopecia.

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      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 2 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  137 upvotes 8 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

      in Female  42 upvotes 3 years ago
      User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.