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natural substance from Neem tree with medicinal and pesticidal properties
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glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
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research Syphilis: today
Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.
research Hair root studies in patients suffering from primary and secondary syphilis
Syphilis patients showed abnormal hair root changes, with no difference between primary and secondary stages.
research Syphilis: A great imitator
Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.
research Pink scaling papules and plaques on the palms, soles, chest, abdomen, and extremities
The woman likely has secondary syphilis, treatable with penicillin.
research 31-Year-Old Woman With Chronic Daily Headache and Alopecia
A woman's chronic headaches and hair loss were cured by treating her syphilis.
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5 / 1000+ resultscommunity The dread shed is obliterating my hair (22M). Been on treatment for about 1.5-2 months. First 8 pics are from a month ago and the rest are my current state. Will this regrow?
A 22-year-old is experiencing significant hair shedding and is using multiple treatments, including oral and topical minoxidil, finasteride, topical dutasteride, ketoconazole shampoo, and considering adding RU58841 and stemoxydine. Others advise patience, suggesting sticking to finasteride and minoxidil for at least a year before evaluating results, as initial shedding is normal and adding too many treatments can be counterproductive.
community 21M, Dermatologist prescribed only Minoxidil
A 21-year-old was diagnosed with early-stage androgenetic alopecia and prescribed only minoxidil 5% and ketoconazole shampoo by a dermatologist, who advised against finasteride for now. The user is skeptical about starting minoxidil due to concerns about increased hair loss.
community 31M started 0.25mg Finasteride 1.5mg finasteride in mid January 2026
A 31-year-old male started using 1.25mg oral Minoxidil and 0.25mg Finasteride in January 2026 to address hair thinning. Users suggest increasing doses and considering additional treatments like topical Minoxidil, microneedling, or switching to dutasteride for better results.
community A Short Recap on PP405 and AAD 2026
PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.
community What is next for pp405 in phase 2b?
PP405 is progressing to Phase 2b trials, with results expected in late 2025 or early 2026, and potential Phase 3 trials in 2026. Some users experienced side effects from finasteride and are hopeful for PP405 as an alternative treatment.