This study found that in androgenetic alopecia patients, there is enhanced expression of type 2 TGF-β and type II receptors in hairfollicles, suggesting a link to hair growth cycle changes.
This study found that increased expression of type 2 TGF-β and type II receptor was observed in the bald vertex area of hairfollicles from androgenetic alopecia patients, suggesting a role in catagen induction.
This review discusses recent advances in understanding the pathogenesis of autoimmune alopecia areata and reports no new clinical results; it highlights potential for developing more effective treatments.
18 citations
,
October 1978 in “The journal of investigative dermatology/Journal of investigative dermatology”
This study found that excess vitamin A induced stable glandular morphogenesis and mucous metaplasia in embryonic mouse vibrissa follicles, even after switching to standard medium.
PP405 is ineffective for miniaturized, fibrosed hairfollicles in androgenetic alopecia. AMP303 may activate hairfollicle stem cells, but minoxidil and finasteride are still the main treatments.
The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.
PP405 shows promise in activating dormant hairfollicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.
A user shared their hair regrowth progress using Dutasteride, topical Minoxidil, Spironolactone, and Estradiol Valerate injections as part of hormone replacement therapy for transitioning. They experienced significant hair improvement and personal satisfaction but caution against this approach for non-transitioning individuals due to irreversible changes.
PP405 is considered as a potential hair regrowth treatment, but users are skeptical due to past product failures. They compare it to Minoxidil and Finasteride, questioning its effectiveness and the intentions of pharmaceutical companies.
What is a hair transplant?A hair transplant is a surgical procedure that relocates hair follicles to areas of thinning.
What are the risks and side effects of FUE hair transplants?Providers describe most FUE side effects, such as swelling, redness, numbness and shock loss, as temporary, but FUE is surgery and the same sources report pain, infection, folliculitis and small permanent donor-site scars. Longer-lasting problems, including visible donor-area thinning or poor graft growth, are possible and are not covered by this provider survey.