121 citations
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January 1991 in “Acta dermato-venereologica”
In this study, terbinafine reached high concentrations in stratum corneum and sebum after oral administration, with drug levels remaining above fungicidal concentrations for over three weeks.
January 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences”
In this hospital-based study, researchers found that serum ferritin levels were significantly lower in individuals with acne compared to healthy controls, suggesting a possible link between iron deficiency and acne pathogenesis.
44 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism”
This study concluded that although RBP4 and adiponectin levels are associated with visceral fat, they do not independently contribute to the development of PCOS.
14 citations
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January 2020 in “Advances in Dermatology and Allergology”
This study found that elevated serumlevels of IL-15 in active alopecia areata patients are correlated with disease severity, suggesting it plays a role in disease pathogenesis.
The user has been using liposomal topical finasteride since late 2022, progressively increasing the dose, but DHT serumlevels remain largely unchanged. Despite using finasteride, minoxidil, microneedling, and ketoconazole, hair condition has neither improved nor worsened.
Dutasteride mesotherapy may stabilize hair loss and improve hair without significantly affecting serum DHT levels, but it can still have systemic effects. Users discuss using topical and oral dutasteride, with some experiencing side effects and considering hair transplants.
A 23-year-old male has been using finasteride and topical minoxidil for 14 months with slight improvement, but recent shedding led him to switch to a new minoxidil formulation without success. He is considering using topical RU58841 or dutasteride to better address scalp DHT, as his bloodwork shows high total testosterone and mid-range DHT levels.
The reduction in scalp oiliness is likely due to finasteride reducing DHT levels and the use of ketoconazole shampoo. The combination of these treatments may have decreased sebum production.
Switching from finasteride to a generic dutasteride led to unexpectedly high DHT levels, prompting a switch to a reputed brand and consideration of softgel capsules for better absorption. The user plans to retest DHT levels and may return to finasteride if issues persist.
Can a lash-growth serum like bimatoprost actually work for your scalp?Bimatoprost (Latisse) is approved for eyelashes, not the scalp; two Allergan phase 2 trials in men with androgenetic alopecia posted results to ClinicalTrials.gov but were never published in a peer-reviewed journal, so scalp use remains off-label and experimental.