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Glossary Follicular Infundibulum

upper part of hair follicle where sebum exits

The follicular infundibulum is the upper part of a hair follicle, extending from the skin's surface down to the point where the sebaceous (oil) gland opens into the follicle. This region is crucial for the passage of sebum and dead skin cells to the skin's surface, and its blockage can lead to conditions like acne.

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Research

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research Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of antiacne agents

88 citations , July 2001 in “British journal of dermatology/British journal of dermatology, Supplement”

This study reported that antimicrobial and topical retinoid therapies led to significant changes in the lipid profiles of sebaceous follicular infundibulum, with increased triglycerides and ceramide subfractions observed.

research Recurrent inverse necrotizing infundibular crystalline folliculitis

1 citations , April 2024 in “Journal of Cutaneous Pathology”

This article presents a case of spontaneous, recurrent necrotizing infundibular crystalline folliculitis in the inguinal region and suggests unknown etiology possibly linked to microbiome and sebaceous gland dysfunction.

research Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct

16 citations , July 2018 in “Experimental Dermatology”

This study suggests that the transcription factor Gata6 plays a role in maintaining the structure of the upper hair follicle and may be implicated in conditions marked by its abnormal expansion, such as acne or cystic diseases.

research Preliminary findings suggest hidradenitis suppurativa may be due to defective follicular support

6 citations , April 2013 in “British Journal of Dermatology”

This article reviews various histological features of hidradenitis suppurativa and proposes discrepancies with previous nomenclature, reporting no new clinical findings; the authors highlight the need for revised understanding.

research Proteome Analysis of Human Sebaceous Follicle Infundibula Extracted from Healthy and Acne-Affected Skin

62 citations , September 2014 in “PLoS ONE”

This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Sebaceous filaments / blackheads on scalp - are they a cause of MPB or a symptom?

in Research/Science 1 upvotes 2 months ago

Sebaceous filaments or blackheads on the scalp are not a cause of hair loss; it's more likely due to hormonal factors, particularly in androgen-sensitive areas like the temples and crown. The user is using topical finasteride, minoxidil, and tretinoin for treatment.

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Clinics

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Hair Transplant
Australian Hair & Scalp Clinics-Hair Regrowth by Herbal Follicular ActivationMelbourne, VIC · AU

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