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research Frontal Fibrosing Alopecia and Increased Scalp Sweating: Is Neurogenic Inflammation the Common Link

15 citations , January 2015 in “Skin Appendage Disorders”

This report discusses a series of patients with frontal fibrosing alopecia experiencing increased scalp sweating, which the authors hypothesize may be related to local skin inflammation affecting sweat gland activity.

Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp

research Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp

January 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)”

This study evaluated 129 patients with androgenetic alopecia and identified an inflammatory pattern of perifollicular infiltration linked to treatment resistance. Targeting both hormonal and immune pathways improved outcomes for 67% of patients, suggesting inflammation may play a role in some cases of stubborn hair loss.

research 917 Frontal fibrosing alopecia scalp profiling links Th1/Th2 and JAK3 activation with fibrosis and loss of follicular stem cells

April 2019 in “Journal of Investigative Dermatology”

Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.

Two Different Trichoscopic Patterns of Mid-Frontal Scalp in Patients with Frontal Fibrosing Alopecia and Clinical Features of Androgenetic Alopecia

research Two different trichoscopic patterns of mid-frontal scalp in patients with frontal fibrosing alopecia and clinical features of androgenetic alopecia

2 citations , January 2017 in “Przegla̧d dermatologiczny”

This study identified two distinct trichoscopic patterns in the mid-frontal scalp of patients with frontal fibrosing alopecia who also display clinical features of androgenetic alopecia.

research Trichoscopy of Frontal Fibrosing Alopecia Affecting Black Scalp: A Literature Review

1 citations , May 2024 in “Skin Appendage Disorders”

In this study, researchers analyzed trichoscopy findings in black patients with FFA to aid in precise diagnosis and treatment, highlighting the importance of understanding disease characteristics to improve hair care in this group.

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community Is it normal for scalp texture and appearance to change where hair is lost?

in Transplants 9 upvotes 9 months ago

The conversation discusses changes in scalp texture and appearance in areas of hair loss, with concerns about the suitability of these areas for hair transplants. Users mention issues like fibrosis, inflammation, and thinner skin, advising caution and consultation with clinics before proceeding with transplants.

community The Real Reason For Hair Loss?

8 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

community Why does the same hormone grow your beard and destroy your hairline?

44 upvotes 4 months ago

DHT promotes beard growth but causes scalp hair loss due to inflammation and fibrosis. Treatments like finasteride and minoxidil help with hormonal signals and blood flow but don't address underlying inflammation.

community TCA 35% chemical peel, don't try this shit at home.

11 upvotes 7 months ago

The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

community Ultrasound can show you if your hair will ever grow back

in Research/Science 41 upvotes 5 months ago

Ultrasound imaging can non-invasively detect active and inactive hair follicles, inflammation, and fibrosis, potentially reducing unnecessary biopsies. It may help assess hair growth potential and diagnose scalp issues, but some users believe in trying treatments regardless of ultrasound results.

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