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This study reports a unique case of coinheritance of BRCA2 and CYLD pathogenic variants in a man with metastatic malignant cylindroma, suggesting that recognizing such genetic profiles in rare conditions can provide new treatment options, including the potential use of therapies targeting BRCA deficiency.

Different scalp conditions can lead to hair loss or tumors, with treatments varying from creams to surgery; early detection is crucial.

Cylindromas likely originate from hair follicle stem cells, not sweat glands.

A woman had 13 non-cancerous cysts on her scalp successfully removed in one surgery.

This review discusses various scalp infections, infestations, and neoplasms but reports no new clinical findings; the authors emphasize the diversity of diseases from different origins.