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research Amino Acid Compositions of Human Hair Fibrous Protein Components Purified with Two‐dimensional Electrophoresis

4 citations , December 1989 in “The Journal of Dermatology”

This study suggests that the amino acid composition of fibrous proteins in normal human hair is similar to that of stratum corneum proteins, particularly in cysteine and glycine content.

research Electrophoretic analysis of human hair keratins

4 citations , December 1995 in “Anthropologischer Anzeiger”

This study reports that electrophoretic patterns of hair keratins are more similar among family members than unrelated individuals, potentially aiding genetic studies.

research Rice Bran Polysaccharides: Structure, Modification, Bioactivity, and Application Potential in Food and Health Systems

June 2026 in “Foods”

This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.

research Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?

6 citations , August 2017 in “Physiological Research”

This study suggests that setipiprant's inhibitory effect on aldose reductase may contribute to its anti-inflammatory properties, adding a possible mechanism beyond its known action on the prostaglandin D2 receptor.

research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity

13 citations , October 2017 in “Bioorganic & Medicinal Chemistry”

This study found that compound 3, a tetrahydropyridoindole carboxymethylated at position 5, significantly inhibited sorbitol accumulation in both rat eye lenses and tissues affected by diabetes, indicating its potential as a lead compound for ALR2 inhibition.

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learn acetyl methionine

learn Botox

What’s the science behind Botox injections for androgenetic alopecia? Small published studies and a 2025 meta-analysis report hair-count gains from scalp botulinum toxin injections, but nearly all of them lack control groups, and reviewers of the same literature call the evidence low-quality; the treatment is off-label and not approved for hair loss anywhere.

learn Glycerin

What’s the difference between vegetable glycerin and synthetic glycerin in hair products? Vegetable glycerin is plant-derived, while synthetic glycerin is petroleum-based, but both are chemically identical.

Community Join

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community That's quite funny if you as me

40 upvotes 3 days ago

Finasteride use and its potential side effects, including erectile dysfunction and post-finasteride syndrome (PFS), with discussions on lifestyle factors and the influence of anxiety. Some users argue that PFS is not well-documented, while others share personal experiences of adverse effects.

community What's the point of finasteride if dutasteride exists?

43 upvotes 5 days ago

Finasteride is effective for hair loss with fewer side effects and quicker clearance compared to dutasteride, which is more potent but has a longer half-life and potentially more side effects. Users suggest starting with finasteride and considering dutasteride only if more hair retention is needed and side effects are manageable.

community What's the proper way to use a derma stamp?

104 upvotes 2 weeks ago

A user is seeking advice on using a derma stamp for hair loss treatment, alongside minoxidil and finasteride. Recommendations include cleaning the scalp, using alcohol or hypochlorous acid for sterilization, starting with a needle length of 0.5mm, and stamping once a week.

community What's your unpopular opinion?

56 upvotes 2 weeks ago

Minoxidil is criticized for being inconvenient and ineffective compared to finasteride, with some users experiencing issues like flaking and greasy hair. Alternatives like adenosine are suggested, and the effectiveness of minoxidil can be improved with tretinoin and dietary changes.

community Let’s be real, does infrequent smoking really accelerate MPB and/or cause health issues?

10 upvotes 2 weeks ago

Smoking infrequently is unlikely to significantly impact hair loss or health, especially when using treatments like finasteride and minoxidil. Genetics play a larger role in hair loss, and low smoking frequency is not considered a major risk.

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