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GlossaryS100 Proteins (S100)

calcium-binding proteins involved in cell regulation and signaling

S100 Proteins are a family of calcium-binding proteins involved in various intracellular and extracellular functions, such as regulation of protein phosphorylation, enzyme activities, and cell growth and differentiation. They are implicated in several diseases, including cancer, neurodegenerative disorders, and inflammatory conditions, making them significant both in basic biological research and clinical diagnostics.

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Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

72 citations , June 2001 in “Journal of Investigative Dermatology”

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

research Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer

62 citations , December 2007 in “Journal of biological chemistry/The Journal of biological chemistry”

A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.

research S100A6: Molecular Function and Biomarker Role

50 citations , September 2023 in “Biomarker Research”

S100A6 is important for cell functions and can help diagnose and treat diseases.

research Significance of the S100A4 Protein in Psoriasis

45 citations , July 2009 in “Journal of Investigative Dermatology”

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

research Ultrastructural Localization of S100A3, a Cysteine-Rich, Calcium Binding Protein, in Human Scalp Hair Shafts Revealed by Rapid-Freezing Immunocytochemistry

40 citations , April 1999 in “Journal of Histochemistry & Cytochemistry”

S100A3 protein is mainly found in specific parts of human hair cells.

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community What's people's thoughts on Fluridil in 2023

in Treatment 6 upvotes 1 year ago

Fluridil is discussed as a potential topical alternative for hair loss for those experiencing side effects from finasteride. Some people have tried higher concentrations, but there's no clear consensus on its effectiveness.

community Hairline itch when hairline’s receding

in Chat 80 upvotes 1 month ago

Hair loss treatments like finasteride, dutasteride, minoxidil, and RU58841. Users discuss "DHT itch" at receding hairlines and suggest using dutasteride or ketoconazole shampoo for relief.

community Anyone else’s loved ones just blatantly gaslight you over your hair ?

in Finasteride/Dutasteride 196 upvotes 2 years ago

User discusses resentment towards people who dismissed their hair loss concerns and continued to do so even after a specialist confirmed it. Others share similar experiences and discuss the impact of hair loss on self-esteem and societal perceptions.

community In my opinion baldness is more prevalent now and it's being ignored..

in Chat 236 upvotes 2 years ago

The conversation is about the prevalence of baldness among young men and the potential factors contributing to it. Specific treatments mentioned include minoxidil and finasteride.

community Goodbye y'all, it's been a journey but have accepted where I'm at

in Update 219 upvotes 2 years ago

The conclusion of this conversation about hair loss is that the user, y00sh420, tried various treatments including a $700 lllt helmet, topical minoxidil and finasteride, spectraDNC, and micro needling, but did not achieve the desired results. They have decided to stop trying until a cure for male pattern baldness is found. Other users expressed different opinions on hair loss treatments.

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