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GlossaryMice (Rodents)

small rodents often used in biological and medical research

Mice, also known as murine rodents, are small mammals commonly used in scientific research due to their genetic, biological, and behavioral similarities to humans. They are particularly valuable in studies related to hair and alopecia because their genetic makeup can be easily manipulated to model human diseases, allowing researchers to investigate the underlying mechanisms and potential treatments.

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research Regression of Pathological Changes Induced by Long-Term Administration of Contraceptive Steroids to Rodents

20 citations , June 1985 in “Toxicologic Pathology”

Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.

research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents

127 citations , December 2007 in “Journal of Investigative Dermatology”

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

research Molecular and Functional Aspects of the Hairless (Hr) Gene in Laboratory Rodents and Humans

126 citations , October 1998 in “Experimental Dermatology”

The hr gene is crucial for skin and hair health, with mutations causing hair disorders.

research Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids

61 citations , April 2018 in “Frontiers in endocrinology”

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

The Effect of Active Hexose Correlated Compound in Modulating Cytosine Arabinoside-Induced Hair Loss, and 6-Mercaptopurine- and Methotrexate-Induced Liver Injury in Rodents

research The Effect of Active Hexose Correlated Compound in Modulating Cytosine Arabinoside-Induced Hair Loss, and 6-Mercaptopurine- and Methotrexate-Induced Liver Injury in Rodents

14 citations , August 2009 in “Cancer epidemiology”

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

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community Eirion ET-02( RS 5441) managed to defeat rodents, finally

in Technology 67 upvotes 9 months ago

ET-02 (RS 5441) shows promising results for hair growth, performing better in humans than in mice. There is debate over the effectiveness compared to minoxidil, with some users wanting more detailed data.

community Realistically, how much PP405 will cost?

in Treatment 30 upvotes 9 months ago

PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.

community I think I’m actually winning (take ur drugs lads)

in Progress Pictures 121 upvotes 1 week ago

A 24-year-old male experienced hair loss and successfully treated it using a combination of Finasteride, Dutasteride, and Oral Minoxidil. He reported no side effects and plans to continue the treatment to maintain his hair.

community Methods Of Staying Safe On Ru58841 - My 2 Cents

in Research/Science 22 upvotes 9 months ago

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

community Hey guys I’m in desperate need for opinions from long term finasteride users

in Finasteride/Dutasteride 25 upvotes 2 years ago

Whether taking finasteride and dutasteride can cause penile shrinkage, with long-term users providing their personal experiences.

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