7 citations
,
January 2022 in “Animal Reproduction” This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.
17 citations
,
December 2010 in “Journal of Investigative Dermatology” This study found that higher levels of the protein Flii were associated with enhanced hair follicle regeneration and longer hair fibers in a mouse model.
96 citations
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April 2007 in “Journal of Investigative Dermatology” In this study, co-grafting human keratinocytes with murine dermal papilla-enriched cells produced hair follicle-like structures, but without regular hair formation, suggesting anomalous folliculogenesis.
37 citations
,
December 2003 in “Reproductive Toxicology” The researchers reported that the rat Hershberger assay reliably detected endocrine-disrupting effects of finasteride, procymidone, and 17α-methyltestosterone, validating the assay's sensitivity for identifying hormonal activity.
23 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses rodent models of alopecia areata and suggests they are crucial for understanding the autoimmune mechanisms and potential treatments but reports no new clinical results.
January 2025 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia” In this study, researchers observed that telogen hair was more prevalent than anagen hair in both male and female agoutis over a one-year period in Teresina-PI, regardless of dry or rainy seasons, with no significant differences in dermal follicular volume between the sexes.
October 2024 in “Российский физиологический журнал им И М Сеченова” This study explores the neurobiology and genetics of barbering (hair and whisker biting) in laboratory rodents, and its potential links to stress, aggression, grooming, and stereotypic behaviors, highlighting its significance in experimental work with these animals.
March 2023 in “Scientific Reports” In this rodent model study, the researchers reported that using low-intensity focused ultrasound with phenytoin enhanced its anti-epileptic efficacy by disrupting plasma protein binding in a region-specific manner, reducing seizure frequency and duration.
January 2020 in “Indian Journal of Pharmaceutical Sciences” This review discusses rodent models of human hair loss and highlights the potential of traditional medicinal plants as hair growth promoters, but reports no new clinical results.
January 2023 in “Indian Journal of Forensic and Community Medicine” This report describes two cases of thallium poisoning with gastrointestinal symptoms, peripheral neuropathy, and alopecia, which were effectively treated using activated charcoal, potassium chloride, and hemodialysis.
28 citations
,
September 2013 in “Biogerontology” 5 citations
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April 2014 in “Journal of Lipid Research” This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.
2 citations
,
August 2022 in “Middle East Fertility Society Journal” This study found that combining fructose and DHT in rats successfully mimicked the clinical phenotypes of non-lean PCOS, providing a novel rodent model for this condition.
1 citations
,
January 2014 in “PubMed” This study found that PK11195 treatment weakened exploratory behavior in two strains of mice, while finasteride and indomethacin decreased exploration in laboratory rodents regardless of species.
This study found that in both rodents and humans, knee laxity increased at certain phases of the reproductive cycle due to sex-steroid influence, particularly under high levels of estrogen and progesterone.
27 citations
,
March 2008 in “Cell stress & chaperones” This study found that localized administration of heat or certain stress protein inducers effectively prevented chemotherapy-induced hair loss in rodent models without affecting chemotherapy efficacy.
April 2019 in “Journal of Investigative Dermatology” Researchers created a new mouse model for studying scleroderma.
127 citations
,
December 2007 in “Journal of Investigative Dermatology” This review examines regenerative hair waves and complex hair cycle domains in transgenic mice, highlighting how these dynamic processes contribute to skin regeneration and the physiological regulation of organs, but reports no new experimental results.
126 citations
,
October 1998 in “Experimental Dermatology” This review provides an overview of the hairless gene in mice and humans, discussing its structure, expression, and implications for understanding skin physiology and human disorders related to gene disruption, but it reports no new empirical findings.
61 citations
,
April 2018 in “Frontiers in endocrinology” This review discusses the local production and role of sex steroids in the hippocampal neurons of adult rodents and reports no new experimental findings.
13 citations
,
June 2005 in “PubMed” In this study, 33% of mice treated with polyphenol extract from green tea showed significant hair regrowth, while no control group mice exhibited hair growth.
February 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that distinct spiny hair morphologies in rodents arose independently multiple times but did not link the Ecdysoplasin A receptor gene mutation that affects human hair to these variations.
7 citations
,
June 2012 in “Journal of dairy science” This study found that topical application of bovine milk polar lipids accelerated hair cycle progression in mice, showing potential for use in cosmetic products.
5 citations
,
January 2016 in “Journal of Molecular Histology” Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.
5 citations
,
August 2011 in “Journal of Dermatological Science” In this study, researchers found that dentin sialoprotein and phosphophoryn are present in rat and mouse hair follicles, suggesting these proteins may play a role in hair follicle development, similar to their role in dentin mineralization.
March 2025 in “Journal of Endocrinology and Metabolism” This study found that while rat models treated with letrozole and dihydrotestosterone exhibit altered sterol, leukotriene, and steroid hormone profiles similar to human PCOS, significant differences remain.
October 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study examined lipid changes in rat models of polycystic ovarian syndrome, finding that letrozole and dihydrotestosterone treatments led to some lipid alterations similar to human PCOS, while other changes were unique to the models.
This study suggests that keratin 15 and Id3 proteins play distinct roles in epithelial and dermal cell activities during the regeneration stages of rat vibrissae hair follicles.
20 citations
,
June 1985 in “Toxicologic Pathology” In this study, prolonged high-dose steroid treatment in rats caused several pathological changes, some of which regressed, particularly improvements in mammary gland tumors and pituitary-related symptoms, after stopping treatment.
17 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that anthralin and mechlorethamine were the most effective therapies among those tested in AA-affected rodent models, providing a basis for further analysis of their mechanisms in Alopecia Areata.