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Glossary Rhabdomyolysis

rapid muscle breakdown releases harmful proteins into the bloodstream

Rhabdomyolysis, often referred to as "rhabdo," is a serious medical condition characterized by the rapid breakdown of damaged skeletal muscle tissue. This process releases muscle cell contents, including a protein called myoglobin, into the bloodstream, which can lead to kidney damage and other complications. Common causes include severe physical exertion, trauma, infections, and certain medications or drugs.

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research Valproate-Associated Transaminitis and Rhabdomyolysis

2 citations , April 2023 in “Curēus”

This study presents a case of a 24-year-old man who developed mild transaminitis and rhabdomyolysis within 24 hours of starting valproic acid for seizures, with symptom resolution following drug cessation.

Risk of Rhabdomyolysis from 5-Alpha Reductase Inhibitors

research Risk of rhabdomyolysis from 5-α reductase inhibitors

6 citations , January 2018 in “Pharmacoepidemiology and Drug Safety”

In this study, 5-α reductase inhibitors were not significantly linked to increased rhabdomyolysis risk, but they may raise the risk of myopathy and myositis in men aged 66 and older.

research A phase 2a randomized, placebo-controlled study to evaluate the efficacy and safety of the oral Janus kinase inhibitors ritlecitinib and brepocitinib in alopecia areata: 24-week results

138 citations , March 2021 in “Journal of the American Academy of Dermatology”

This study found that treatment with ritlecitinib or brepocitinib was effective in improving scalp hair loss for patients with alopecia areata over 24 weeks compared to placebo.

research Haff disease associated with the ingestion of the freshwater fish Mylossoma duriventre (pacu-manteiga)

11 citations , January 2013 in “Revista Brasileira De Terapia Intensiva”

This article reports a case of rhabdomyolysis in a patient two hours after consuming the freshwater fish Mylossoma duriventre, suggesting a possible link to Haff disease from an unidentified toxin.

research Paraphenylenediamine hair dyeing nephropathy: a case report and review of literature

4 citations , January 2018 in “Urology & Nephrology Open Access Journal”

This case report details an instance of acute kidney injury following the inhalation of hair dye during a hairstyle session.

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