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research Qualitative study for finasteride detection in the prostate delivered by reversible inhibition of sperm under guidance – Prostate hair (RISUG-PH^™) vas injectable implant

April 2025 in “Journal of Reproductive Healthcare and Medicine”

This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.

research Adverse effects of common medications on male fertility

77 citations , June 2015 in “Nature Reviews Urology”

This article reviews the effects of various medications on male fertility, noting that while commonly used drugs can mostly have reversible impacts, conclusive human evidence remains limited.

research The association of medications and supplements with human male reproductive health: a systematic review

4 citations , October 2023 in “Fertility and Sterility”

This review highlights potential negative impacts of certain medications on male fertility, such as hormonal disruption and germ cell toxicity, emphasizing the importance of clinicians being aware of these effects to advise on safer alternatives.

research What should it take to describe a substance or product as 'sperm-safe'

58 citations , March 2013 in “Human Reproduction Update”

This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.

research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis

253 citations , April 2014 in “Drugs”

This review discusses the preclinical and clinical data on teriflunomide for multiple sclerosis, highlighting its selective action on immune cells without causing clinical immune suppression, and provides no new clinical results.

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community My balding/recovery rollercoaster story so far. I've regrown and lost my hair like 8 times in the last few years. Developed gyno but luckily it's reversible for me. M27

5 upvotes 4 years ago

A 27-year-old man experienced hair regrowth and gynecomastia from finasteride, leading to a cycle of stopping and restarting the treatment. He is considering gyno surgery and consulting an endocrinologist as potential solutions.

community Can we stop fear mongering with finasteride

in Finasteride/Dutasteride 285 upvotes 11 months ago

Finasteride is effective for hair loss but can cause sexual dysfunction and mental health issues in some users, leading to a polarized debate on its risks. Some switch to alternatives like Dutasteride or topical treatments to avoid side effects.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 2 years ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community Help! Gyne after 20 years of taking Dut

in Finasteride/Dutasteride 39 upvotes 2 years ago

A 43-year-old experienced gynecomastia after 20 years of taking dutasteride and 7.5mg oral minoxidil. Suggestions include consulting an endocrinologist, checking hormones, and considering Nolvadex or DIM supplements.

community Study: You can safely conceive on Dutasteride

in Research/Science 95 upvotes 1 year ago

Dutasteride is considered safe for conception, with semen concentrations being too low to cause harm. Users discuss switching between dutasteride and finasteride, with some experiencing side effects like acne and heart issues, and advice is given to maintain a consistent treatment regimen.

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