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GlossaryRete Ridges (Rete Pegs)

downward projections of the epidermis into the dermis

Rete ridges, also known as epidermal ridges or rete pegs, are the downward projections of the epidermis into the dermis. They interlock with the upward projections of the dermis, called dermal papillae, to strengthen the connection between these two skin layers, enhancing the skin's structural integrity and resistance to shear forces. This interlocking structure is crucial for maintaining skin stability and facilitating nutrient exchange between the layers.

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research Full Thickness Wound Healing in the Lanyu Pig

April 2016 in “Journal of Investigative Dermatology”

Full thickness wounds on Lanyu pigs' skin resulted in abnormal skin structure and function due to changes in molecular expression patterns.

research Regeneration of Rete Ridges in Lanyu Pig (Sus Scrofa): Insights for Human Skin Wound Healing

15 citations, January 2019 in “Experimental Dermatology”

Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.

research A Nude Mouse Model of Hypertrophic Scar Shows Morphologic and Histologic Characteristics of Human Hypertrophic Scar

47 citations, November 2012 in “Wound repair and regeneration”

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

research Common Baldness in Women

9 citations, December 1981 in “International Journal of Dermatology”

The document concludes that early diagnosis is key for treating common baldness in women, but reassurance is often the best approach as hair thinning can be a normal part of aging.

research Skin Biology: Understanding Biological Targets for Improving Appearance

1 citations, January 2009 in “Elsevier eBooks”

The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.

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community microneedle, any long term users damage?

in Microneedling 35 upvotes 5 months ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.