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research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )

9 citations , January 2014 in “Molecular Genetics and Metabolism Reports”

This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.

research The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

165 citations , September 2001 in “Genes & development”

This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.

research A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits

5 citations , June 2023 in “BMC genomics”

This study found that a specific genetic mutation in the Fgf5 gene may contribute to the long-hair trait in Angora rabbits by reducing the binding capacity of the FGF5 protein.

research Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice

32 citations , January 2010 in “Journal of Dermatological Science”

In this study, Waved-5 mice with reduced EGFR signaling showed nearly normal skin and hair follicle function but experienced a transient reduction in subcutaneous fat.

research Congenital hair loss disorders: Rare, but not too rare

41 citations , November 2011 in “The Journal of Dermatology”

This review identifies genetic mutations associated with congenital hair loss disorders in Japanese populations, particularly highlighting common LIPH gene mutations linked to woolly hair/hypotrichosis, and reports no new clinical results.

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Community Join

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community Got a 3,5K graft hair transplant at 22.

in Transplants 120 upvotes 6 months ago

A 22-year-old had a 3,500 graft hair transplant to restore his original hairline and improve density, while using dutasteride and oral minoxidil to manage hair loss. He believes being proactive with medication prevented further loss and allowed for a successful transplant.

community If PP405 works it will be fkn impossible to buy it.

103 upvotes 10 months ago

PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Can hanging upsidedown regrow hair?

897 upvotes 3 months ago

Hanging upside down is suggested as a method to increase blood flow to the scalp for hair growth, but its effectiveness is questioned. Treatments mentioned include minoxidil, finasteride, biotin, estrogen, and scalp massage.

community 9 Months post FUE surgery hair result. 4052 grafts, 10130 hairs transplanted

1093 upvotes 1 year ago

The individual had a hair transplant in Turkey with 4052 grafts, resulting in significant hair growth and increased confidence. They use finasteride, rosemary oil, and vitamins, and are pleased with the natural-looking results, encouraging others to consider similar treatments.

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Learn

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learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

How does KY19382 actually stimulate dormant hair follicles to grow again? KY19382 stimulates dormant hair follicles by reactivating the Wnt/β-catenin signaling pathway.
What is KY19382, and how is it different from minoxidil or finasteride? KY19382 is an experimental hair growth compound targeting the Wnt/β-catenin pathway, unlike minoxidil and finasteride.

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Thymosin Beta 4

learn TDM-105795

What is TDM-105795, and why is it being studied as a potential product for hair loss and hair growth support? TDM-105795 is an experimental drug aimed at treating androgenetic alopecia to promote hair growth.

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