75 citations
,
May 2013 in “Journal of the American Academy of Dermatology” This review examines skin symptoms, diagnosis, and treatment of zinc deficiency in children, proposing a classification system but reporting no new clinical results.
65 citations
,
January 2009 in “Annals of Dermatology” In this study, oral zinc supplementation for twelve weeks increased serum zinc levels in alopecia areata patients with low zinc, showing positive hair regrowth in 66.7% of participants, though this was not statistically significant.
56 citations
,
January 2013 in “International journal of trichology” This case report suggests that zinc supplements may be necessary to improve hair loss in hypothyroidism patients being treated with thyroxine.
53 citations
,
October 1978 in “Archives of dermatology” This study reports two cases of acquired zinc deficiency presenting with skin symptoms such as hair loss and acrodermatitis, suggesting these manifestations may help in diagnosing zinc deficiency in humans.
30 citations
,
June 2006 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, oral zinc sulphate was found to cause hair hypopigmentation and significantly inhibit eumelanogenesis in mice.
27 citations
,
March 2012 in “Dermatologic Therapy” In this study, all five patients with zinc deficiency-related hair loss experienced improvement or recovery of their condition after receiving oral zinc treatment.
22 citations
,
December 2013 in “Molecular biology of the cell” This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.
12 citations
,
July 1979 in “International Journal of Dermatology” This article reviews the clinical manifestations and contributing factors of acute zinc depletion syndrome, reporting no new results but discussing prevention and treatment strategies.
10 citations
,
May 1986 in “Experientia” This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.
5 citations
,
May 2020 in “Diagnostics” This study involving male patients with androgenic alopecia found that a higher baseline zinc plasma level, specifically above 10 µmol/L, may predict the success of treatment with 5% topical minoxidil, correlating with increased hair density and diameter in the parietal area.
3 citations
,
June 2019 in “Journal of Bangladesh Society of Physiologist” This study found that patients experiencing hair loss had significantly lower serum levels of zinc and copper compared to healthy controls.
3 citations
,
September 2005 in “Experimental dermatology” This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.
2 citations
,
July 2022 in “Asian Journal of Microbiology, Biotechnology & Environmental Sciences” This review highlights zinc's crucial role in both plant growth and human health, while noting the widespread problem of zinc deficiency in various soils, but reports no new findings.
1 citations
,
February 2022 in “Open Access Macedonian Journal of Medical Sciences” This study found that lower zinc serum levels may contribute to premature hair graying in college students at Universitas Sumatera Utara.
January 2024 in “Biological trace element research” In this study, isotretinoin treatment for acne vulgaris was associated with changes in plasma phosphorus, potassium, magnesium, and zinc levels, potentially affecting kidney function and contributing to side effects like fatigue and dry skin.
April 2023 in “Acta Poloniae Pharmaceutica” This study found that using Urtica cannabina extract shampoo led to increased levels of copper, zinc, and iodine in the scalp hair of Mongolian women, along with improvements in hair growth, diameter, and density compared to a regular shampoo.
May 2026 in “Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology” The researchers reported that zinc carbonate nanoparticles stabilized with polyvinylpyrrolidone did not show local irritant or skin-resorptive effects in preclinical tests on rabbits and rats.
December 2023 in “Journal of nutritional science and vitaminology” This study in mice found that a zinc-deficient diet suppressed body weight gain and increased kidney and cecum tissue weight without decreasing serum alkaline phosphatase activity. Additionally, zinc deficiency caused alopecia and intestinal changes in C57BL/6J mice, potentially affecting nutritional status.
1 citations
,
May 2025 in “International Journal of Applied Pharmaceutics” This study formulated a nanogel with Bangkal bark extract that showed moderate antibacterial activity against Propionibacterium acnes, with the F3 formulation (8% extract) achieving the highest inhibition zone of 8 mm, suggesting potential as a natural acne treatment.
188 citations
,
October 2012 in “The AAPS Journal” This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.
16 citations
,
September 2018 in “Journal of Molecular Liquids” This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.
3 citations
,
February 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study suggests that a herbal oil formulation combining various plant and oil ingredients may effectively promote healthy hair growth and address concerns like baldness, dryness, and dandruff, supported by favorable evaluations of its physical and chemical properties.
2 citations
,
January 2025 in “International Journal of Pharmaceutical Research and Applications” This study formulated an herbal shampoo using natural extracts and compared its physicochemical properties, such as pH and foam consistency, with commercial shampoos, finding that both performed similarly in conditioning tests conducted with twenty volunteers.
May 2026 in “International Journal of Pharmacognosy and Life Science” This research evaluated a polyherbal powder shampoo using natural ingredients, finding it to be a stable, effective, and safe alternative to chemical-based shampoos, with no irritation and good usability.
February 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this review, researchers explored the potential of herbal shampoos as effective and safe alternatives to conventional anti-dandruff treatments, highlighting that polyherbal formulations may offer comparable or superior benefits with fewer side effects.
November 2025 in “International Journal for Research in Applied Science and Engineering Technology” This study describes the creation of a herbal hair oil using natural ingredients like curry leaves and hibiscus and found that the F1 oil formulation effectively reduces hair fall, removes dandruff, improves scalp blood flow, prevents early graying, and combats fungal infections.
November 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This study evaluated an herbal hair dye made from plant-based ingredients, finding it stable, non-toxic, and effective in providing lasting color, improving hair texture, and reducing hair fall, making it a viable and eco-friendly alternative to chemical dyes.
October 2025 in “Current Pharmaceutical Research” This study evaluated a new herbal shampoo made from traditional plants and found it to have effective cleansing properties, moderate foam stability, and environmental safety, suggesting it as a favorable natural alternative to synthetic shampoos.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” This abstract outlines the concept and benefits of herbal hair masks, emphasizing that these plant-based formulations, including ingredients like Bhringraj and Hibiscus, may enhance scalp health and hair strength without adverse effects, but does not report specific research findings.
October 2024 in “International Journal of Pharma Professional’s Research (IJPPR)” This study developed and characterized Quercetin-loaded nanogels, finding that they showed promising potential for enhanced drug delivery and stability in treating Alopecia, with an optimized batch achieving a drug release of 95.32% over 12 hours.