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A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.

Researchers made a mouse model with curly hair and hair loss by editing a gene.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.

Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

Monitor for early signs of azathioprine toxicity and check blood counts regularly.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Men who start balding at age 20 may have a higher chance of getting aggressive prostate cancer.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

Certain genetic markers on chromosome 20 are linked to hair loss in the Han Chinese from Yunnan.

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

sPLA2-X is crucial for normal hair growth and follicle health.

Different types of dog hair loss are linked to problems starting the hair growth phase and early hair cycle ending.

Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.

Environmental factors like smoking, UV exposure, and poor diet contribute to hair loss and graying, and lifestyle changes can help manage it.

The document concludes that non-endocrine alopecia in pets varies in treatment effectiveness and often has a poor prognosis, especially in cats.

The document concludes that skin and hair changes in small animals are often due to hormonal imbalances and recommends regular baths and antibiotics for associated infections.