18 citations,
July 2015 in “Drug Healthcare and Patient Safety” Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
15 citations,
November 2023 in “Immunity & ageing” TLR4 is important in aging-related diseases and could be a new treatment target.
14 citations,
September 2021 in “Journal of Inflammation Research” Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.
11 citations,
May 2012 in “Genesis” Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
8 citations,
January 2019 in “International Journal of Trichology” Early diagnosis and a combination of treatments, including minoxidil and finasteride, are recommended for managing hair loss in India.
6 citations,
May 2021 in “Clinical Chemistry and Laboratory Medicine” Different ACE2 gene versions may affect COVID-19 impact based on age and suggest some hair loss drugs could be potential treatments.
5 citations,
January 2016 in “Skin appendage disorders” Frontal fibrosing alopecia might be linked to autoimmune diseases.
5 citations,
November 2003 in “Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic” The exact causes of baldness are not fully understood, limiting treatment options.
2 citations,
January 2023 in “Pharmaceuticals” Natural products and phytochemicals may help with hair regrowth, but more research is needed.
1 citations,
January 2024 in “International journal of molecular sciences” The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
1 citations,
March 2022 in “Irish Journal of Medical Science” Men with androgenetic alopecia and hypertension may experience more severe COVID-19.
1 citations,
January 2019 in “Journal of Research in Medical Sciences” Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.
January 2024 in “Biology of sex differences” Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
August 2023 in “Drug Design Development and Therapy” Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
June 2023 in “Pharmaceuticals” Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.
April 2022 in “International journal of respiratory and pulmonary medicine” People with lower levels of free testosterone tend to have worse COVID-19 outcomes.
November 2021 in “Research Outreach” Low testosterone levels may lead to more severe COVID-19 outcomes.
January 2011 in “Humana Press eBooks” The document discussed hair loss causes and treatments but didn't give a final summary.
May 2021 in “F1000Research” The treatment led to denser, thicker hair growth and less hair loss.
January 2009 in “Hair transplant forum international” Dr. Rodney Sinclair uses a detailed grading system to diagnose female pattern hair loss, recommends daily spironolactone and minoxidil for treatment, and believes genetics play a role in the condition.
The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.
28 citations,
April 2010 in “British Journal of Dermatology” Genetic marker rs12558842 strongly linked to male hair loss.
24 citations,
July 2011 in “British Journal of Dermatology” Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
71 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
52 citations,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
12 citations,
December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
6 citations,
November 2017 in “Skin appendage disorders” Topical botanical lotion increases hair density and improves quality of life in women with hair loss.
35 citations,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.