Search
for

    Glossary Wnt5a

    protein crucial for cell signaling in hair follicle development

    Wnt5a is a protein that plays a crucial role in cell signaling pathways, which are essential for various developmental processes in the body, including the growth and repair of tissues. In the context of hair biology, Wnt5a is involved in regulating hair follicle development and cycling, making it significant for understanding conditions like alopecia, where hair growth is disrupted.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduction and Targeted Therapy · 2022 · 318 citations
    2. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    3. Wnt signaling induces epithelial differentiation during cutaneous wound healing BMC Cell Biology · 2006 · 159 citations
    4. WNT Signaling in Disease Cells · 2019 · 144 citations
    5. Targeting the Wnt pathways for therapies Molecular and cellular therapies · 2014 · 112 citations
    6. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017 · 105 citations
    7. Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis Genes & development · 2010 · 95 citations
    8. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020 · 86 citations
    9. Wnt signaling in skin organogenesis Organogenesis · 2008 · 72 citations
    10. Wnt signaling induces epithelial differentiation during cutaneous wound healing Organogenesis · 2015 · 66 citations
    11. Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth Scientific Reports · 2014 · 61 citations
    12. WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis Burns & Trauma · 2022 · 56 citations
    13. Wnt signaling: the good and the bad Acta Biochimica et Biophysica Sinica · 2008 · 48 citations
    14. Liposomal honokiol promotes hair growth via activating Wnt3a/β-catenin signaling pathway and down regulating TGF-β1 in C57BL/6N mice Biomedicine & Pharmacotherapy · 2021 · 31 citations
    15. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016 · 26 citations
    16. Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system Journal of Tissue Engineering and Regenerative Medicine · 2015 · 23 citations
    17. Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice International journal of medical sciences · 2013 · 19 citations
    18. Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review) Molecular Medicine Reports · 2021 · 18 citations
    19. Wnt5a Suppresses β-catenin Signaling during Hair Follicle Regeneration International Journal of Medical Sciences · 2016 · 16 citations
    20. Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases Journal of Cellular Biochemistry · 2019 · 16 citations
    21. Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway Oncotarget · 2017 · 11 citations
    22. Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway International Journal of Biological Sciences · 2023 · 9 citations
    23. Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development Development · 2022 · 7 citations
    24. Differential effects of Wnt5a on the proliferation, differentiation and inflammatory response of keratinocytes Molecular Medicine Reports · 2017 · 6 citations
    25. A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 5 citations
    26. Dynamic Wnt5a expression in murine hair follicle cycle and its inhibitory effects on follicular Asian Pacific journal of tropical medicine · 2014 · 3 citations
    27. N6-Methyladenosine modification (m6A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats Animal Bioscience · 2022 · 2 citations
    28. Is Wnt5a overexpression sufficient for generating a psoriasis‐like phenotype in transgenic mice? Experimental Dermatology · 2014 · 2 citations
    29. Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway Oxidative Medicine and Cellular Longevity · 2022 · 2 citations
    30. Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations