417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
44 citations,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
August 2024 in “Frontiers in Public Health” Alopecia Areata severely impacts mental health, causing anxiety and depression, affecting quality of life.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
21 citations,
September 2013 in “Current medicinal chemistry” HAC and BAC improve skin targeting and reduce diffusion without causing irritation.
61 citations,
May 2016 in “Scientific reports” The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
2 citations,
May 2021 in “Research Square (Research Square)” Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
1 citations,
December 2022 in “Pharmaceutics” Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
159 citations,
July 2014 in “Molecular pharmaceutics” New micelle nanocarriers deliver Tacrolimus more effectively to skin layers for psoriasis treatment than the current Protopic ointment.
June 2020 in “Aesthetic Surgery Journal” Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.
1 citations,
November 2022 in “Pharmaceutical research” The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
17 citations,
April 2017 in “International Journal of Biological Macromolecules” Monoolein-alginate beads help heal wounds by controlling moisture and effectively delivering adenosine to the skin.
33 citations,
October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
2 citations,
January 2018 in “Biomolecules & therapeutics” Polyamidoamine dendrimers can change the strength and direction of electroosmotic flow through the skin, affecting drug delivery.
6 citations,
June 2019 in “Skin Research and Technology” Finasteride works for hair loss by maintaining existing hair follicles, not reversing miniaturization.
4 citations,
January 2023 in “Experimental dermatology” Skin thickness decreases and structural changes occur with both ageing and sun exposure in certain skin types.
7 citations,
June 1992 in “The Journal of Dermatologic Surgery and Oncology” Hair transplantation is a viable treatment for some types of female hair loss, with careful donor assessment and attention to psychological factors.
2 citations,
May 2015 in “Journal of Cosmetic and Laser Therapy” Hair follicles can survive for a few days before transplant but are less viable over time.
May 1993 in “Medical Clinics of North America” Surgical hair replacement is a viable option for male pattern baldness when done with proper planning and realistic expectations.
4 citations,
May 2019 in “Skin Research and Technology” Finasteride helps hair growth but stopping it causes faster hair loss.
15 citations,
August 2002 in “British Journal of Ophthalmology” Intralesional cidofovir might be a viable alternative treatment for certain conditions.
17 citations,
January 2007 in “Annals of Medicine” Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.
1 citations,
September 2023 in “Drug development and industrial pharmacy” The optimized formula promotes significant hair growth and could be a viable hair loss treatment.
6 citations,
May 2009 in “Cell transplantation” Green tea component EGCG helps keep rat skin grafts viable longer.
4 citations,
January 2023 in “Skin health and disease” Blocking Janus kinase 1 helps stop inflammation and regrow hair, making it a good treatment for hair loss from alopecia areata.
1 citations,
October 1996 in “Dermatologic clinics” Adiponectin reduces inflammation and bone loss in joint replacements.
January 2016 in “프로그램북(구 초록집)” The revised BASP classification for hair loss is less accurate and harder to use but could still be a viable option.
August 2002 in “British journal of ophthalmology” Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a viable alternative.
45 citations,
April 2013 in “Dermatologic surgery” Hair transplantation might work for some people with frontal fibrosing alopecia, but more research is needed.