July 2023 in “Chinese Journal of Dermatology” Vascular endothelial growth factor might be involved in common hair loss.
June 2023 in “Italian Journal of Medicine” This study found that urotensin II promoted proliferation and VEGF secretion in rat dermal papilla cells by activating the Wnt-β-catenin signaling pathway, with the effect being reversible by a Wnt inhibitor.
April 2023 in “Clinical and experimental dermatology” This case study highlights the rare occurrence of scarring and nonscarring alopecia following vascular occlusion from dermal filler injections, with the researchers suggesting that a combined treatment including hydroxychloroquine might improve outcomes for this complication.
This study examined 144 patients with COVID-19 in Guatemala and found a significant link between skin manifestations, especially those with vasculonecrotic damage, and a higher likelihood of severe to critical illness.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that intracrine androgen signaling, mediated by steroid 5α-reductase, is essential for optimal decidualization and vascular development in the endometrium during pregnancy, indicating potential targets for improving age-related fertility issues.
February 2020 in “Research Square (Research Square)” In this study, skin tags in Irish adults with morbid obesity were associated with higher blood pressure, higher HbA1c levels, and a greater prevalence of diabetes and hypertension, suggesting increased cardiovascular risk.
June 2019 in “Journal of Hypertension” This study found that magnesium deficiency in rats led to elevated diastolic blood pressure and altered vascular responses, although the mechanisms remain unclear.
May 2018 in “Dermatologic Surgery” This overview details the Dermatologic Surgery journal's comprehensive focus on cosmetic and reconstructive skin surgery, but it presents no new research findings.
March 2018 in “Benha Journal of Applied Sciences” This study found that serum VEGF levels were lower in women with telogen effluvium compared to healthy controls, indicating a possible role of VEGF in the condition's pathogenesis.
December 2015 in “Vascular Pharmacology” Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
This study found that a modified scaffold with VEGF165 genetically modified hair follicle stem cells significantly promoted blood vessel growth and wound healing in rats, suggesting its potential as a skin substitute in clinical settings.
February 2014 in “PubMed” This study reports that high-purity rHFSCs with strong proliferation and high VEGF165 expression can be efficiently obtained, facilitating tissue engineering applications like artificial hair follicles and skin construction.
Botulinum toxin-A may increase hair growth and reduce hair loss in men with baldness, and injecting near blood vessels can improve pain relief and last longer.
January 2010 in “Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai” This study found that Huoxue Bushen Mixture increased VEGF expression and the proliferation of dermal papilla cells, suggesting it may promote hair growth compared to control treatments in rats.
December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” This study observed that thymosin beta 4 and VEGF have similar expression patterns in various human tissues, suggesting a role in angiogenesis and organ function.
December 2009 in “생명과학회지” This study found that thymosin β4 is highly expressed in multiple human tissues and may play a role in organ function and angiogenesis through co-localization with VEGF.
January 2009 in “International Journal of Pathology and Clinical Medicine” This article reviews the role of VEGF in hair follicle growth and cycle modulation but concludes that its specific molecular mechanisms in hair follicle growth remain unclear.
January 2007 in “Linchuang pifuke zazhi” In this study, licorice was found to significantly increase VEGF protein synthesis and mRNA expression in human dermal papilla cells, which may promote hair growth.
In this study, latanoprost was found to stimulate VEGF protein synthesis in human dermal papilla cells, suggesting it may contribute to promoting hair growth.
January 2006 in “Chinese Journal of Aesthetic Medicine” In this study, lipo-minoxidil was found to increase vascular endothelial growth factor expression in the skin of C57BL/6 mice more than standard minoxidil formulations.
January 1999 in “대한피부과학회지” This study found that VEGF, produced by human dermal papilla cells, can promote hair growth in vitro without increasing the proliferation of dermal papilla cells.
January 2023 in “International journal of research publications” According to this study, rice bran oil was as effective as 2% minoxidil in improving hair growth parameters, such as VEGF expression, follicle diameter, and hair length, in Wistar rats treated for 21 days, showing potential for preventing hair thinning associated with aging.
19 citations
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October 2023 in “Bioengineering” This study reviewed the efficacy of mechanical fractionation techniques to produce tissue stromal vascular fraction (tSVF) and found that tSVF injections are particularly effective for conditions like osteoarthritis and wound healing, with centrifugation before fractionation improving isolation efficiency regardless of preparation method.
10 citations
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May 2021 in “Expert Opinion on Drug Delivery” This study found that CoQ10 formulated in transethosomes showed improved penetration and a better clinical response in treating androgenic alopecia compared to CoQ10 solution.
113 citations
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July 2020 in “International Journal of Molecular Sciences” This review suggests that allogenic adipose stem cell and extracellular matrix transplants may be safe and effective for various medical conditions, based on available studies.
40 citations
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March 2018 in “Aesthetic Surgery Journal” This study found that a single injection of platelet-rich stroma significantly increased hair density in men with androgenetic alopecia within 6 to 12 weeks, with no reported side effects.
36 citations
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July 2022 in “Stem Cell Research & Therapy” This study concluded that using adipose tissue-derived stromal vascular fraction significantly improved acne scars by increasing collagen content and skin thickness compared to nanofat alone.
30 citations
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July 2017 in “Stem cells and cloning” This study found that scalp injection of fat enriched with stem cells may offer a promising alternative for treating early genetic alopecia in both men and women.
25 citations
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May 2020 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” This article discusses the potential benefits of platelet-rich plasma injections in ovarian tissue to improve reproductive outcomes in IVF for older individuals and proposes a mechanism to enhance embryo ploidy rescue, but reports no new clinical results.
25 citations
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May 2020 in “Aesthetic Surgery Journal” In this systematic review, tSVF-based therapy demonstrated favorable outcomes for various pathologies, including aged skin and osteoarthritis, with low incidence of adverse events, while highlighting the need for further research into optimal protocols and mechanisms of action.