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    Glossary Vertex

    topmost point of the scalp, often called the crown

    In the context of hair and alopecia, the term "vertex" refers to the topmost point of the scalp, often called the crown. This area is particularly significant in discussions of hair loss, as it is a common site for thinning and balding, especially in conditions like male pattern baldness (androgenetic alopecia). For professionals, the vertex is a critical area to assess when diagnosing and planning treatment for hair loss.

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    1. Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3 Journal of The American Academy of Dermatology · 2000 · 26 citations
    2. Effect of minoxidil topical foam on frontotemporal and vertex androgenetic alopecia in men: a 104‐week open‐label clinical trial Journal of The European Academy of Dermatology and Venereology · 2015 · 20 citations
    3. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    4. Dermatoscopic Evaluation of Central Centrifugal Cicatricial Alopecia Beyond the Vertex Scalp JAMA dermatology · 2020 · 9 citations
    5. Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3 Journal of The American Academy of Dermatology · 2000 · 3 citations
    6. Serum androgens and prostate-specific antigen levels in androgenetic alopecia: is there a difference between frontal and vertex baldness? Journal of The European Academy of Dermatology and Venereology · 2017 · 1 citations
    7. Prevalence of fronto-vertex baldness and its association with family history of androgenetic alopecia in Korean men using basic and specific classification Journal of Dermatology · 2016 · 1 citations
    8. Vertex Overload: A Thermo Mechanical and Metabolic Framework for Androgenetic Alopecia Zenodo (CERN European Organization for Nuclear Research) · 2025
    9. Eficacia y seguridad del plasma rico en plaquetas intralesional comparado con minoxidil al 5% tópico en el tratamiento de la alopecia androgenética masculina con afectación en vértex Revista del Centro Dermatológico Pascua · 2022
    10. Case Report: Paired vertex-occipital assessment reveals donor-area involvement in diffuse unpatterned alopecia Frontiers in Medicine · 2026
    11. Vertex Overload: A Thermo Mechanical and Metabolic Framework for Androgenetic Alopecia Zenodo (CERN European Organization for Nuclear Research) · 2025
    12. Supplementary Figure 2 from Male-Pattern Vertex Baldness Trajectories, Chest Hair Patterns, and Odds of Overall and Aggressive Prostate Cancer 2024
    13. Acquired non-scarring vertex alopecia in three women revealing trichotillomania: Diagnostic accuracy of trichoscopy Our Dermatology Online · 2023
    14. 313 Different polyamine levels in the vertex and occipital hair of pattern hair loss patients Journal of Investigative Dermatology · 2019
    15. Response: Finasteride's Effect on Frontal and Vertex Hair Loss Dermatologic Surgery · 2010
    16. Vertex Accentuation in Female Pattern Hair Loss in Asians DOAJ (DOAJ: Directory of Open Access Journals) · 2016
    17. Vertex Accentuation in Female Pattern Hair Loss 2016
    18. Structural and Immunocytochemical Characterization of Keratinization in Vertebrate Epidermis and Epidermal Derivatives International review of cytology · 2006 · 82 citations
    19. Vertebral epidermal transamidases Biochimica et Biophysica Acta (BBA) - Protein Structure · 1974 · 49 citations
    20. A comparative single-cell transcriptomic atlas for diverse populations of vertebrate hair cells bioRxiv (Cold Spring Harbor Laboratory) · 2026
    21. Use of Verteporfin with Dermal Wounding to Regenerate New Hair in Androgenetic Alopecia Journal of Dermatology Research and Therapy · 2025
    22. Use of Verteporfin to Regrow Hair and Reduce Fibrosis after Transplantation Journal of Dermatology Research and Therapy · 2025
    23. Inhibition of the Hippo pathway by verteporfin reduces the proliferation and stemness of rat hair follicle neural crest stem cells under hypoxia FASEB BioAdvances · 2025
    24. What is the best sampling region for endocrine hair analysis? A comparison between the posterior vertex and occipital region and recommendation for standardization Psychoneuroendocrinology · 2025 · 9 citations
    25. 564 Vertex and Occipital Intermediate and Terminal Hair Follicles from Androgenetic Alopecia Patients are Differentially Affected by Testosterone Ex Vivo Journal of Investigative Dermatology · 2022
    26. ESDR564 – Vertex and Occipital Intermediate and Terminal Hair Follicles from Androgenetic Alopecia Patients are Differentially Affected by Testosterone Ex Vivo 2022
    27. Terrestrial vertebrates have two keratin gene clusters; striking differences in teleost fish European Journal of Cell Biology · 2005 · 47 citations
    28. Rare Case of Cutis Vertex Gyrata Journal of Medical Science And clinical Research · 2025
    29. Embryonic keratinization in vertebrates in relation to land colonization Acta Zoologica · 2008 · 44 citations
    30. Parallels between vertebrate cardiac and cutaneous wound healing and regeneration npj Regenerative Medicine · 2018 · 23 citations