32 citations,
November 2016 in “Journal of Dental Research” Pannexin 3 is important for bone formation and the development of bone cells.
192 citations,
March 1998 in “British Journal of Dermatology” Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.
23 citations,
September 2011 in “Journal of Dermatological Science” Red LED light helps mouse hair grow by increasing growth factors from skin cells.
19 citations,
May 2020 in “Cells” Substance from human umbilical cord blood cells promotes hair growth.
16 citations,
October 2018 in “Biochemical and Biophysical Research Communications” Sildenafil, often used for erectile dysfunction, may help hair growth.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” Minoxidil nanoparticles improve hair growth more effectively than regular minoxidil.
June 2005 in “Key Engineering Materials” Using hydrogels to slowly release growth factors can effectively boost hair growth in mice.
30 citations,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
5 citations,
April 2022 in “Pharmaceutics” The study demonstrated that a 5% minoxidil nanoparticle (MXD-NPs) formulation significantly enhanced hair growth in C57BL/6 mice compared to conventional minoxidil solutions. MXD-NPs, with a mean particle size of 139.8 nm, delivered 7.4 times higher concentrations of minoxidil to the hair bulge, leading to increased activation of hair follicle epithelial stem cells (HFSC). This resulted in higher mRNA and protein levels of hair growth factors IGF-1 and VEGF, and noticeable hair growth effects within 8 days. The findings suggest that MXD-NPs are more effective in promoting hair growth by targeting hair follicles, offering a promising treatment for androgenetic alopecia (AGA).
8 citations,
December 2014 in “Clinical and Experimental Dermatology” CTE and FPHL are different hair loss types with unique causes.
3 citations,
February 2021 in “Experimental dermatology” Dermal papilla microtissues could be useful for initial hair growth drug testing.
1 citations,
March 2009 in “Journal of Investigative Dermatology” Lipase H is important for hair follicle function and shaping hair fibers.
December 2015 in “Vascular Pharmacology” Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.
182 citations,
August 2018 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
87 citations,
April 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.
75 citations,
October 2002 in “Journal of Dermatological Science” Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
59 citations,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
55 citations,
May 2017 in “Current stem cell research & therapy” Using fat-derived stem cells for hair loss treatment is safe and effective, improving hair growth and patient satisfaction.
53 citations,
February 2020 in “Expert Opinion on Pharmacotherapy” Finasteride and minoxidil work best together for hair loss.
47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
44 citations,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
38 citations,
July 2021 in “ACS Nano” Microneedles help treat hair loss by improving hair surroundings and promoting growth.
33 citations,
September 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
33 citations,
January 2006 in “Journal of Dermatological Science” A long-acting Vitamin C derivative helps hair grow by stimulating cells and increasing growth factors.
29 citations,
March 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
26 citations,
May 2017 in “Lasers in Medical Science” Laser therapy and hair growth factors significantly improve hair density in male baldness.
23 citations,
November 2017 in “Stem cell investigation” Platelet lysate is more effective than activated autologous platelet-rich plasma or saline in improving hair growth after hair restoration surgery.
17 citations,
February 2018 in “Journal of Cosmetic and Laser Therapy” The QR 678 hair growth treatment was safe and effective for hair regrowth in men and women.
15 citations,
May 2020 in “BMC complementary medicine and therapies” Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
15 citations,
August 2018 in “Life Sciences” Diabetex improves diabetic wound healing better than metformin.