research New-Onset Systemic Lupus Erythematosus Beginning as Class V Lupus Nephritis After COVID-19 Vaccination
COVID-19 vaccination may trigger lupus in some people.
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research Biofeedback Treatment for Dysfunctional Voiding Diagnosed in Adulthood
Biofeedback treatment for dysfunctional voiding in adults showed no symptom improvement.
research Does Post-Void Residual Volume Predict Worsening Urological Symptoms in Patients with Multiple Sclerosis?
Post-void residual volume does not predict worsening urological symptoms in multiple sclerosis patients.
research Salicylate Ingestion And Idiopathic Hair Loss
Avoiding aspirin may prevent hair loss.
research Felinine Excretion in Domestic Cat Breeds: A Preliminary Investigation
Shorthaired and hairless cat breeds excrete more felinine than longhaired breeds.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution
Longer contact time increases minoxidil absorption, but doesn't affect metabolism.
research A Case of Severe Autoimmune Hemolytic Anemia After Receipt of First Dose of SARS-CoV-2 Vaccine
An 84-year-old man developed severe anemia after his first COVID-19 vaccine shot, improved with treatment, and was advised against a second dose.
research Increased Polyamine Concentrations in the Hair of Cancer Patients
Hair can be used to measure cancer-related chemicals noninvasively.
research Molecular, immunological, enzymatic and biochemical studies of coproporphyrinogen oxidase deficiency in a family with hereditary coproporphyria.
The study focused on a 27-year-old woman with hereditary coproporphyria, characterized by recurrent renal pain, dark urine, and hair loss, but no photosensitivity. Elevated urinary porphyrin metabolites and fecal studies confirmed the diagnosis, with decreased coproporphyrinogen oxidase activity at 35% of normal levels. Her mother and sisters were identified as heterozygous carriers of the condition, showing reduced enzyme activity up to 50%. A novel mutation was discovered in the coproporphyrinogen oxidase gene, involving a cytosine to thymine transversion at nucleotide position 854. Immunological studies indicated decreased enzyme protein concentrations in the patient and her family members.
research Office Management of the Adolescent with Diabetes Mellitus
The document recommends a team-based approach and personalized care for managing diabetes in teenagers.
research Glycol Ethers and Neurodevelopment: Investigating the Impact of Prenatal Exposures
Exposure to certain glycol ethers during pregnancy may be linked to lower verbal comprehension in children.
research Neuroma of Radial Nerve After Surgical Correction of Secondary Lesion of Humeral Diaphyseal Fracture
Surgery to fix a broken upper arm bone can sometimes lead to nerve damage.
research Prevalence of Respiratory Disorders in Patients With Cleft Lip and Palate: Systematic Review
People with cleft lip and palate often have respiratory problems.
research Human Hair: An Important Biological Matrix of Interest
Human hair is a significant sample for various tests in clinical, nutritional, archaeological, and forensic studies.
research Case 3: The Hypothermic Newborn
The infant with a urea cycle disorder improved with treatment and a liver transplant.
research Fate of Mimosine, Concentration of Blood Metabolites and Thyroid Hormones of Sheep Fed with Leucaena and Glyricidia Leaf Meal
Feeding sheep up to 30% Leucaena leaf meal does not harm their blood metabolites and thyroid hormones.
research Anhidrotic Effect of Intradermal Injections of Botulinum Toxin—A Comparison of Different Products and Concentrations
Different botulinum toxin products and concentrations can effectively reduce sweating, itching, bladder pressure, hair loss, and muscle spasms.
research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostate patients more likely to have hair loss.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
research Clinical Manifestations and Management of Acute Thallium Poisoning
Thallium poisoning causes pain, hair loss, and nerve issues, treatable with hemoperfusion and hemodialysis.
research Trichorrhexis Nodosa
The study on trichorrhexis nodosa (TN) involved 49 patients, with 26 experiencing scalp hair involvement, and 20 of these cases linked to excessive hair trauma. Additionally, 23 patients had TN in genito-inguinocrural or multiple sites, all experiencing pruritus. The condition often improved with less traumatic hair care or pruritus control. The research did not support the theory of TN being a metabolic defect, as shown by urine chromatography and hair analysis. The findings highlighted trauma as a significant factor, with in vitro experiments reproducing TN through mechanical stress, identifying it as a common cause of unexplained hair loss.
research A Successfully Treated Case of Criminal Thallium Poisoning
A woman poisoned with thallium was successfully treated with activated charcoal and Prussian blue.
research Ganoderma Lucidum as an Inhibitor of Testosterone-Induced Prostatic Hyperplasia in Rats
Ganoderma lucidum may help treat enlarged prostate in rats.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Tardily Accelerated Neurologic Deterioration in Two-Step Thallium Intoxication
Thallium poisoning can cause worsening nerve damage and vision loss without typical symptoms.
research Haff Disease Associated With The Ingestion Of The Freshwater Fish Mylossoma Duriventre (Pacu-Manteiga)
Eating pacu-manteiga fish can cause Haff disease, leading to severe muscle damage.
research Finasteride-Induced Pseudoporphyria
Finasteride caused blisters on hands and feet.